Summary
Chromatographic behaviour of phenolic compounds is studied on the ethyleneglycol methacrylate gel Spheron and on ion-exchangers produced by the chemical modification of this gels (cation exchanger Spheron S and anion exchanger Spheron DEAE) as compared to octadecyl silica. The hydrophobic effects obviously predominate in the retention mechanism on Spherons in aqueous methanolic mobile phases, but a selectivity differring from the behaviour on octadecyl silica was found for a number of phenolic compounds This is due to interactions with the functional groups in the unmodified and modified Spheron materials and may be utilized for the separation of phenols by liquid chromatography.
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P. Jandera, J. Churáček, J. Čáslavský andM. Vojáčková, Chromatographia, under publication.
P. Jandera, J. Churáček andD. Szabó, Chromatographia, under publication.
F. J. Schabron, R. J. Hurtubise andH. F. Silver, Anal. Chem.50, 1911 (1978).
K. Callmer, L. E. Edholm andB. E. F. Smith, J. Chromatogr.136, 45 (1977).
L. E. Edholm andK. Callmer, J. Chromatogr.137, 363 (1977).
S. Hussain, P. Kunzelmann andH. Schildknecht, J. Chromatogr.137, 53 (1977).
S. Hussain andM. Kifayatulla, J. Chromatogr.168, 517 (1979).
P. Jandera andJ. Churáček, J. Chromatogr.86, 423 (1973).
L. Olsson, I. Renne andO. Samuelson, J. Chromatogr.123, 355 (1976).
P. G. Pifferi, L. Baldassari andO. Gandolfi, J. Chromatogr.88, 381 (1974).
K. S. Lee, D. W. Lee andI. S. Chung, Anal. Chem.45, 396 (1973).
M. Popl, V. Dolanský, J. Chromatogr.148, 195 (1978).
L. Olsson andO. Samuelson, J. Chromatogr.106, 139 (1975).
A. F. Cunningham andD. E. Hillman, J. Chromatogr.148, 528 (1978).
V. Dasgupta, J. Pharm. Sci.65, 1706 (1976).
I. Molnár andC. Horváth, Clin. Chem.22, 1497 (1976).
L. A. Sternson andW. J. DeWitte, J. Chromatogr.138, 229 (1977).
W. A. Court, J. Chromatogr.130, 287 (1977).
A. W. Wolkoff andR. H. Larose, J. Chromatogr.99, 731 (1974).
A. A. Qureshi, N. Prentice andW. C. Burger, J. Chromatogr.170, 343 (1979).
J. K. Selkirk, R. G. Croy andH. V. Gelboin, Cancer Res.36, 922 (1976). [Anal. Abstr. 6D39 (1976)].
M. D. Grieser andD. J. Pietrzyk, Anal. Chem.45, 148 (1973).
A. C. Haglund, J. Chromatogr.156, 317 (1978).
M. Jaworski, Chem. Anal. (Warsaw)23, 461 (1978).
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Jandera, P., Churaček, J., Čáslavský, J. et al. Liquid chromatography on unmodified and modified Spheron gels III. Phenolic compounds. Chromatographia 14, 100–106 (1981). https://doi.org/10.1007/BF02279520
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DOI: https://doi.org/10.1007/BF02279520