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Peak symmetry as a measure of column performance in high-performance liquid chromatography

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Summary

During a column-packing method development study, 114 reverse phase and 40 silica gel columns were packed. A relationship between peak symmetry and column efficiency was observed which was found to be useful when evaluating column performance.

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Author notes

  1. R. G. Brownlee

    Present address: Brownlee Labs, 2065 Martin Ave, 95050, Santa Clara, CA, U.S.A.

  2. J. W. Higgins

    Present address: Bio-Rad Laboratories, 32nd Griffin Ave, 94804, Richmond, CA, U.S.A.

Authors and Affiliations

  1. Hewlett-Packard, Ohmstr. 6, D-7500, Karlsruhe 41, German Federal Republic

    R. G. Brownlee

  2. Società Internazionale Ricerche Steroidi, I-20017, Rho (Milan), Italy

    J. W. Higgins

Authors
  1. R. G. Brownlee
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  2. J. W. Higgins
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Brownlee, R.G., Higgins, J.W. Peak symmetry as a measure of column performance in high-performance liquid chromatography. Chromatographia 11, 567–572 (1978). https://doi.org/10.1007/BF02268925

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  • DOI: https://doi.org/10.1007/BF02268925

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