Summary
Different chromatography — mass spectrometry techniques for the analysis of β-agonists have been compared.
Gas chromatography — mass spectrometry (electron impact) has been used, as also has liquid chromatography coupled to the mass spectrometer by either thermospray or electrospray interfaces. The results obtained by the three method were compared in terms of sensitivity, selectivity, and richness of information provided by the analysis. It was found that using electrospray ionization, very powerful analysis could be achieved with high sensitivity, thus providing significant potential for the analysis of β-agonists.
Similar content being viewed by others
References
L. O. Fiems, Ann. Zootech.,36, 271 (1987).
M. C. Dumasia, E. Houghton, J. Chromatogr.,564, 503 (1991).
A. Polettini, M. C. Ricossa, A. Groppi, M. Montagna, J. Chromatogr.,564, 529 (1991).
L. A. Van Gintel, G. W. Stephany, H. J. van Rossum, J. Assoc. Off. Anal. Chem.,75, 554 (1992).
H. J. Forster, K. L. Roninger, E. Ecker, H. Peil, A. Wittrock, Biomed. Environm. Mass Spectrom.,17, 417 (1988).
J. Girault, P. Gobin, J. B. Fourtillan, Biomed. Environ. Mass Spectrom.,19, 80 (1990).
M. S. Leloux, R. A. A. Maes, Biomed. Environ. Mass Spectrom.,18, 137 (1990).
H. Maurer, K. Pfleger J. Chromatogr.,382, 147 (1986).
M. S. Leloux, E. G. De Jong, R. A. A. Maes, J. Chromatogr.,488, 357 (1989).
W. J. Blachflower, D. G. Kennedy, Biomed. Environ. Mass Spetrom.,18, 935 (1989).
M. S. Leloux, W. M. A. Niessen, R. A. M. Van Der Hoeven, Biol. Mass Spectrom.,20 647 (1991).
A. Walhagen, L. E. Edholm, C. E. M. Heeremans, R. A. M. Van Der Hoeven, W. M. A. Niessen, U. R. Tjaden, J. Van Der Greef, J. Chromatogr.,474, 257 (1989).
L. leyssens, C. Driessen, A. Jacobs, J. Czech, J. Raus, J. Chromatogr.,564, 515 (1991).
A. P. Bruins, J. Chromatogr.,554, 39 (1991), and references therein.
R. D. Smith, J. A. Loo, C. G. Edmonds, C. J. Baringa, H. R. Udseth, Anal. Chem.,62, 882 (1990).
J. R. Perkins, C. E. Parker, K. B. Tomer, J. Am. Soc. Mass Spectrom.,3, 139 (1992).
I. M. Johansson, R. Pavelka, J. D. Henion J. Chromatogr.559, 515 (1991).
P. Arpino, Fresenius' J. Anal. Chem.,337, 667 (1990).
P. Arpino, Mass Spectrom. Rev.,9, 631 (1990).
D. Courtheyn, C. Desaever, R. Verhe, J. Chromatogr.,564, 537 (1991).
H. H. D. Meyer, L. Rinke, I. Dürsch, J. Chromatogr.,564, 551 (1991).
W. Haasnoot, M. E. Ploum, R. J. A. Paulussen, R. Schilt, F. A. Huf, J. Chromatogr.519, 323 (1990).
A. L. L. Duchateau, B. H. M. Munsters, G. T. C. Kwakkenbos, R. G. J. Van Leuken, J. Chromatogr.,552, 605 (1991).
J. A. Loo, H. R. Udseth, R. D. Smith, Rapid Comm. Mass Spectrom.,2, 207 (1988).
V. Katta, S. K. Chowdhury, B. T. Chait, Anal. Chem.,63, 174 (1991).
L. Debrauwer, G. Bories, Rapid Comm. Mass Spectrom.,6, 382 (1992).
C. M. Whitehouse, R. N. Dreyer, M. Yamashita, J. B. Fenn, Anal. Chem.,57, 675 (1985).
L. Debrauwer, G. Bories, Anal. Chim. Acta, in press.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Debrauwer, L., Delous, G. & Bories, G. Comparison of various hyphenated chromatography — Mass spectrometry methods for the analysis of β-agonists. Chromatographia 36, 218–224 (1993). https://doi.org/10.1007/BF02263868
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02263868