Summary
The energy of interaction (∈0) between the methylene group and the surface of a sorbent is proposed for use in the quantitative evaluation of the hydrophobicity of a sorbent. A method was developed to determine the ∈0 parameter from chromatographic measurements using the investigated sorbent as the stationary phase and linear methylene-containing homologous series, e.g., alkanols, amino-alkanes, etc., as the test compounds. The effectiveness of this method is demonstrated by using, as examples, a series of bonded stationary phases and a series of cross-linked copolymeric sorbents differing in the concentration of the hydrophobic groups. The proposed method is compared with the Martin rule used extensively in the chromatography of oligomers.
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Pasechnik, V.A., Solovyova, L.Y., Gorbunov, A.A. et al. A chromatographic method for hydrophobicity investigations of sorbents. Chromatographia 28, 258–262 (1989). https://doi.org/10.1007/BF02260771
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DOI: https://doi.org/10.1007/BF02260771