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Investigations on imidazoles 98. Reactions of nitrohaloimidazoles with amino acids

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The reaction of 5-chloro(bromo)-1-methyl(1,2-dimethyl)-4-nitroimidazoles and 4-chloro-1-methyl-5-nitroimidazole with amino acids has been studied. This has enabled a series of N-(4-nitro-5-imidazolyl)- and N-(5-nitro-4-imidazolyl)-substituted amino acids to be synthesized. Esters of some of these acids have been obtained.

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Authors
  1. P. M. Kochergin
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  2. L. A. Reznichenko
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  3. R. N. Gireva
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  4. E. V. Aleksandrova
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Additional information

For Part 97 see [1].

Center for Drug Chemistry, All-Russian Research Institute for Pharmaceutical Chemistry, Moscow 119815. Novokuznetsk Research Institute for Pharmaceutical Chemistry, Novokuznetsk 654034, Russia. Zaporozhye State Medical University, Zaporozhye 330074, Ukraine. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 1, pp. 48–53, January, 1999.

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Kochergin, P.M., Reznichenko, L.A., Gireva, R.N. et al. Investigations on imidazoles 98. Reactions of nitrohaloimidazoles with amino acids. Chem Heterocycl Compd 35, 45–50 (1999). https://doi.org/10.1007/BF02251660

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  • DOI: https://doi.org/10.1007/BF02251660

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