Summary
Diversion of gastric contents away from the duodenum by means of gastrojejunostomy led to increases in Heidenhain pouch secretion in 8 dogs previously subjected to total antrectomy. It is suggested that acid in the duodenum may exert a chronic depressant effect on Heidenhain pouch secretion in the antrectomized dog.
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Andersson, S., andGrossman, M. I. Profile of pH, pressure, and potential difference at gastroduodenal junction in man.Gastroenterology 49:364, 1965.
Brackney, E. L., Thal, A. P., andWangensteen, O. H. Role of duodenum in the control of gastric secretion.Proc Soc Exp Biol Med 88:302, 1955.
Griffen, W. O., Jr., Nicoloff, D. M., Stone, N. H., Castaneda, A., andWangensteen, O. H. The duodenum and the intestinal phase of gastric secretion.Surg Forum 12:301, 1961.
Jones, T. W., Stevenson, J. K., Jesseph, J. E., Nyhus, L. M., andHarkins, H. N. The effect upon free hydrochloric acid production of Heidenhain pouches with variation in size and position of a gastrojejunostomy stoma.Amer J Surg 94: 705, 1957.
Kanar, E. A., Schmitz, E. J., Nyhus, L. M., Moore, H. C., Jr., Sauvage, L. R., Storer, E. H., andHarkins, H. N. Effect of high, low and mediam gastrojejunostomy to the main stomach on Heidenhain pouch secretion.Amer J Physiol 175:167, 1953.
Kanar, E. A., Schmitz, E. J., Sauvage, L. R., Storer, E. H., andHarkins, H. N. The secretory response of the stomach to gastroenterostomy, as measured by a Heidenhain pouch.Surg Forum 3:12, 1952.
Konturek, S., andGrossman, M. I. Effect of perfusion of intestinal loops with acid, fat, or dextrose on gastric secretion.Gastroenterology 49:481, 1965.
Landor, J. H., Porterfield, J. F., andWolff, W. S. The parietal cell response to chronic gastric secretory stimulation.Surg Gynec Obstet 122:61, 1966.
Landor, J. H., Ross, J. L., andGay, G. R. The importance of acid inhibition in the regulation of gastric secretion.AMA Arch Surg 85:695, 1962.
Nicoloff, D. M., Peter, E. T., Sosin, H., andWangensteen, O. H. Duodenal regulation of gastric secretion.Surg Forum 14:341, 1963.
Quintana, R., Kohatzu, S., Woodward, E. R., andDragstedt, L. R. Mechanism of duodenal inhibition of gastric secretion.AMA Arch Surg 89:585, 1964.
Woodward, E. R., El Geziri, M. F., Schapiro, H., andPlzak, L. F. The effect of gastroenterostomy on the gastrin mechanism.AMA Arch Surg 74:694, 1957.
Zubiran, J. M., Kark, A. E., Montalbetti, A. J., Morel, C. J. L., andDragstedt, L. R. Quantitative studies on effect of gastrojejunostomy on gastric secretion.AMA Arch Surg 65:239, 1952.
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Supported by Grant AM 07750-02 from the U. S. Public Health Service.
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Landor, J.H., Alcancia, E.Y. & Fulkerson, C.C. Chronic duodenal inhibition of the intestinal phase of gastric secretion. Digest Dis Sci 11, 918–922 (1966). https://doi.org/10.1007/BF02233079
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DOI: https://doi.org/10.1007/BF02233079