Abstract
Phenolic compounds were determined in methanolic extract from the algal mass of aNostoc muscorum culture. Bioassays with two human pathogens,Candida albicans andStaphylococcus aureus indicated that algal phenolic compounds evoked significant growth inhibition for both species (89.1% and 88.2%, respectively). It is suggested that this strong inhibitory effect is of potential medicinal value.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Accorinti J, de Caire GZ, de Mulé CZ (1974) Sustancias biológicamente activas en cultivos axénicos de Cyanophyta. Biologically active substances from Cyanophyta axenic cultures. Phyton 32: 23–33
Barchi JJ Jr, Norton TR, Furusawa E, Patterson GHL, Moore RE (1983) Identification of a cytotoxin fromTolypothrix byssoidea as tubercidin. Phytochemistry 22: 2851–2852
Barlcay W, Kennish JM, Goodrich VM, Fall R (1987) High levels of phenolic compounds inProchloron species. Phytochemistry 26: 739–743
Caire GZ de, Cano MS, de Mulé MCZ, Halperin DR de, Galvagno M (1987) Action of cell-free extracts and extracellular products ofNostoc muscorum on growth ofSclerotinia sclerotiorum. Phyton 47: 43–46
Caire GZ de, Mulé MCZ de, Accorinti J (1974) Valorición experimental de sustancias biológicamente activas obtenidas de cultivos deAphanothece stagnina (Sprengel) A. Braun (Cyanophyta). Phyton 32: 99–105
Cano MS de, Mulé MCZ de, Caire GZ de, Halperin DR de (1986) Growth control ofStaphylococcus aureus andCandida albicans byNostoc muscorum (Cyanophyta). Phyton 46: 153–156
Cannell RJP, Kellam SJ, Owsianka AM, Walker JM (1987) Microalgae and cyanobacteria as a source of glycosidase inhibitors. J. gen. Microbiol 133: 1701–1705
Cannell RJP, Owsianka AM, Walker JM (1988) Results of a large scale screening programme to detect antibacterial activity from fresh water algae. Br. phycol. J. 23: 41–44
Flores E, Wolk CP (1986) Production by filamentous nitrogen-fixing cyanobacteria of a bacteriocin and of other antibiotics that kill related strains. Arch. Microbiol. 145: 215–219
Gleason FK, Paulson JL (1984) Site of action of natural algicide, cyanobacterin, in the blue-green alga,Synechococcus sp. Arch. Microbiol. 138: 273–277
Halperin DR de, Caire GZ de, Mulé MCZ de, Cano MS de (1979) Influencia de diferentes concentraciones de cloruro de sodio sobre la morfología y el contenido de nitrógeno deAnabaena sphaerica Bornet et Flahault aislada de las Salinas Grandes de Jujuy (Argentina). Physis Sec B 38: 21–28
Mackinney G (1941) Absorption of light by chlorophyll solutions. J. Biol. Chem. 140: 315–322
Mason CP, Edwards KR, Carlson RE, Pignatello J, Gleason FK, Wood JM (1982) Isolation of chlorine-containing antibiotic from the freshwater CyanobacteriumScytonema hofmanni. Science 215: 400–402
Metting B, Pyne JW (1986) Biologically active compounds from microalgae. Enzyme Microb. Technol. 8: 386–394
Mulé MCZ de, Caire GZ de, Accorinti J (1976) Inductores e inhibidores, intra y extracelulares, en cultivos axénicos deAphanothece stagnina (Cyanophyta). Phyton 34: 185–191
Mynderse JS, Moore RE, Kashiwagi M, Norton TR (1977) Antileukemia activity in the Oscillatoriaceae: Isolation of debromoaplysiatoxin fromLyngbya. Science 196: 538–540
Ribéreau-Gayon P (1972) Plant Phenolics. Oliver & Boyd, Edinburgh, 254 pp.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
de Cano, M.M.S., de Mulé, M.C., de Caire, G.Z. et al. Inhibition ofCandida albicans andStaphylococcus aureus by phenolic compounds from the terrestrial cyanobacteriumNostoc muscorum . J Appl Phycol 2, 79–81 (1990). https://doi.org/10.1007/BF02179772
Received:
Revised:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02179772