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Serologische und virologische Untersuchungen bei Atemwegsinfektionen durch Respiratory syncytial virus, Adenoviren und andere Viren

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Zeitschrift für Hygiene und Infektionskrankheiten, medizinische Mikrobiologie, Immunologie und Virologie Aims and scope Submit manuscript

Summary

109 children and 11 adults with acute infections of the respiratory tract were investigated with serological and virological methods; 80 virus infections were found in 65 patients (54%). From other 29 children without serological tests a virus was isolated in 5 cases. Complement-fixation tests with 13 different viral antigens were particularly successful. The following infections were found: respiratory syncytial virus (38), adenoviruses (13), parainfluenza viruses (10), reoviruses (8), influenza A (6), enteroviruses (4), influenza C (2), herpes simplex (2), ornithosis (1), and infectious mononucleosis (1).

Rise and fall of complement-fixing antibodies against respiratory syncytial virus antigen were studied in the whole group of patients. Serum pairs of 3 patients, from whom adenoviruses were recovered, failed to exhibit a CF antibody rise against antigens prepared with type 2+3 or type 4; a rise was demonstrated, however, when these sera were tested against an antigen prepared from the adenovirus isolated from the respective patient.

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Authors and Affiliations

  1. Institut für Hygiene und Mikrobiologie und der Kinderklinik der Universität des Saarlandes, Homburg, Saar

    R. Wigand, H. Bauer, F. Lang & W. Burmeister

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  1. R. Wigand
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  2. H. Bauer
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  3. F. Lang
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  4. W. Burmeister
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Additional information

Die Untersuchungen wurden von der Deutschen Forschungsgemeinschaft in großzügiger Weise unterstützt. Herr Dr. habil. J.Potel (Astawerke) stellte uns Virusantigene zur Verfügung. Wir danken den med.-techn. Assistentinnen E.Baschleben, H.Haefner, H.Kaiser und I.Lamy für ihre Hilfe bei den Untersuchungen.

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Wigand, R., Bauer, H., Lang, F. et al. Serologische und virologische Untersuchungen bei Atemwegsinfektionen durch Respiratory syncytial virus, Adenoviren und andere Viren. Zeitschr. f. Hygiene. 150, 83–93 (1964). https://doi.org/10.1007/BF02162301

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  • DOI: https://doi.org/10.1007/BF02162301

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