Summary
1. When fresh cattle adrenals are perfusedin vitro with Tyrode's solution at 37°C, a spontaneous release of catechol amines takes place. This release is enhanced by the injection of tyramine or β-phenylethylamine. 2. In agreement with earlier observations on isolated medullary granules, β-phenylethylamine is more active than tyramine: 16 µM of β-phenylethylamine, 66 µM of tyramine, and 0.03 µM of acetylcholine release almost equal amounts of catechol amines.
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Forschungs-Stipendiat der Alexander von Humboldt-Stiftung.
Ausgeführt mit Unterstützung der Deutschen Forschungsgemeinschaft.
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Haag, H.W., Philippu, A. & Schümann, H.J. Freisetzung von Brenzcatechinaminen aus der isoliert durchströmten Nebenniere durch Tyramin und β-Phenyläthylamin. Experientia 17, 187–188 (1961). https://doi.org/10.1007/BF02160376
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DOI: https://doi.org/10.1007/BF02160376