Skip to main content
Log in

Bau und Funktion der Nukleolen

  • Published:
Experientia Aims and scope Submit manuscript

Summary

In previous years the composition and function of chromosomes have been analyzed to a considerable extent, in contrast to the small number of investigations that have been made on nucleoli. There exist at present many conflicting opinions about the structure and function of the nucleolus, and therefore a critical survey of the facts and theories about the nucleolar substance appears necessary.

The structure, chemical composition and metabolism of the nucleoli of various cells are described in this publication. The regulation of the size and function of the nucleolus is also discussed.

It is concluded that the size and structure of the nucleolus is organ- and species-specific. A rapid synthesis of RNA and proteins occurs in the nucleolus. After a short interval, this disappears; and it is therefore concluded that the nucleolus must have a high turnover of these substances. The size and function of the nucleoli depends on the energy state of the cytoplasm.

It appears that the nucleolus can synthesize proteins which can be utilized by the chromosomes during their genetic function.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. V. Haecker, Arch. mikr. Anat.42 (1893).

  2. E. Robertis, W. Nowinski, undF. Saez, General Cytology (Saunders Comp. London, 1954).

  3. K. Konopka undH. Ziegenspeck, Protoplasma7, 62 (1929).

    Article  Google Scholar 

  4. Ch. Postelmann undH. Ziegenspeck, Protoplasma11, 298 (1930).

    Article  Google Scholar 

  5. B. Wilson,The Cell in Development and Heredity (New York, 1925).

  6. T. Goda, Fac. Sci. Imp. Univ. Tokyo, Sect. 4,2, 178 (1951).

    Google Scholar 

  7. L. Sharp,Einführung in die Zytologie (Borntraeger, Berlin 1931).

    Google Scholar 

  8. H. Altmann, Z. Naturf.4b, 138 (1949).

    Article  Google Scholar 

  9. T. Caspersson,Cell Growth and Function (Norton, New York 1950).

    Google Scholar 

  10. A. Pollister undC. Leuchtenberger, Nature163, 360 (1949).

    Article  CAS  Google Scholar 

  11. H. Stich undJ. Hämmerling, Z. Naturf.8b, 329 (1953).

    Article  CAS  Google Scholar 

  12. J. Hämmerling, Arch. Protistenk.97, 7 (1944).

    Google Scholar 

  13. E. Küster,Die Pflanzenzelle (Fischer, Jena (1951).

    Google Scholar 

  14. H. Stich, Z. Naturf.6b, 319 (1951).

    Article  CAS  Google Scholar 

  15. H. Altmann, Naturwissenschaften6, 138 (1952).

    Article  Google Scholar 

  16. W. Bernhard, F. Haguenau, A. Gautier undCh. Oberling, Z. Zellf.37, 281 (1952).

    Article  CAS  Google Scholar 

  17. C. Estable undJ. Sotelo, Stain Techn.27, 307 (1952).

    Article  CAS  Google Scholar 

  18. M. Gersch, Z. Zellf.30, 483 (1940).

    Article  Google Scholar 

  19. S. Vincent, Proc. Nat. Acad. Sci.38, 139 (1952).

    Article  CAS  Google Scholar 

  20. H. Callan undS. Tomlin, Proc. Roy. Soc. [B]137, 367 (1950).

    CAS  Google Scholar 

  21. H. Bauer, Z. Zellf.18, 254 (1933).

    Article  Google Scholar 

  22. A. Pollister undC. Leuchtenberger, Nature163, 360 (1949).

    Article  CAS  Google Scholar 

  23. Zum Beispiel:E. Krugelis, Biol. Bull.93, 215 (1947).

    CAS  Google Scholar 

  24. Ch. Landschütz, Exper.6, 232 (1950).

    Google Scholar 

  25. M. Ross undJ. Ely, Exp. Cell Res.2, 339 (1951).

    Article  CAS  Google Scholar 

  26. M. de Nicola, Micr. Sci.90, 391 (1949).

    Google Scholar 

  27. J. Serra undA. Queiroz-Lopes, Chromosoma2, 576 (1944).

    Article  Google Scholar 

  28. H. Swift, Rev. Cytology2, 1 (1953).

    Article  CAS  Google Scholar 

  29. E. Heitz, Planta12, 775 (1931);15, 495 (1931).

    Article  Google Scholar 

  30. B. McClintock, Z. Zellf.21, 284 (1934).

    Article  Google Scholar 

  31. P. Buchner, Arch. mikr. Anat.91, 1 (1918).

    Article  Google Scholar 

  32. E. Wolf,Moderne Biologie, Festschr.Nachtsheim (Berlin, 1950).

  33. H. Bauer, Zool. Jb.56, 239 (1936).

    Google Scholar 

  34. J. Schulz, Cold Spring Harb. Symp. Quant. Biol.12, (1949).

  35. E. Heitz, Planta12, 775 (1931).

    Article  Google Scholar 

  36. W. Beermann, Z. Naturforschg.7, 237 (1952).

    Article  Google Scholar 

  37. E. Heitz, Planta15, 495 (1931).

    Article  Google Scholar 

  38. N. Borsook, C. Deasy, A. Haagen-Smith, G. Keighley undP. Lowy, J. Biol. Chem.184, 529 (1952).

    Article  Google Scholar 

  39. P. Siekevitz, J. Biol. Chem.195, 549 (1952).

    Article  CAS  Google Scholar 

  40. J. Holtfreter, Cop. Cell. Research7, 95 (1954).

    Article  CAS  Google Scholar 

  41. Zum Beispiel:J. Davidson,The Biochemistry of Nucleic Acid (Methuen's Monogr., London 1951).

    Google Scholar 

  42. T. Caspersson, Naturwissenschaften29, 33 (1941).

    Article  CAS  Google Scholar 

  43. Zum Beispiel:S. Smellie,The Nucleic Acids II (Acad. Press, New York 1955), S. 393.

    Google Scholar 

  44. H. Stich undJ. Hämmerling, Z. Naturf.8b, 329 (1953).

    Article  CAS  Google Scholar 

  45. A. Ficq, Exper.9, 377 (1953).

    CAS  Google Scholar 

  46. F. Schrader undC. Leuchtenberger, Exp. Cell. Res.1, 421 (1950).

    Article  CAS  Google Scholar 

  47. F. Haurowitz undJ. Crampton, Exp. Cell. Res. [Suppl.]2, 45 (1952).

    CAS  Google Scholar 

  48. J. Brachet,Nucleic Acids II (Acad. Press, New York 1955), S. 476.

    Google Scholar 

  49. F. Vanderhaeghe undD. Szafarz, Arch. Intern. Physiol. Biochim.63, 267 (1955).

    CAS  Google Scholar 

  50. O. Lindberg undL. Ernster, Protoplasmatologia3A, 4 (1954).

    Google Scholar 

  51. K. Lang undG. Siebert,Der Stoffwechsel, Bd.1 (Springer-Verlag, Berlin 1954), S. 1064.

    Book  Google Scholar 

  52. H. Stich, Z. Naturf.6b, 319 (1951); Chromosoma (1955) (in press).

    Article  CAS  Google Scholar 

  53. H. Stich, Z. Naturf.8b, 36 (1953).

    Article  CAS  Google Scholar 

  54. J. Hämmerling, Rapp. Comm. 8me Congr. intern. Bot., Paris 1954 (im Druck).

  55. J. Hämmerling, Naturwissenschaften33, 337 und 361 (1946); Rev. Cytology2, 475 (1953).

    Article  Google Scholar 

  56. J. Brachet,The Nucleic Acids II (Acad. Press, New York 1955), S. 476.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Stich, H. Bau und Funktion der Nukleolen. Experientia 12, 7–14 (1956). https://doi.org/10.1007/BF02156979

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02156979

Navigation