Skip to main content
SpringerLink
Log in

Untersuchungen zur Meningokokkenträgerquote

  • Published:
Zeitschrift für medizinische Mikrobiologie und Immunologie Aims and scope Submit manuscript

    We’re sorry, something doesn't seem to be working properly.

    Please try refreshing the page. If that doesn't work, please contact support so we can address the problem.

Summary

Investigations of 726 soldiers, students and technical assistants during an interepidemic period have shown that about 40% of the soldiers and 20% of both other groups harbored meningococci in their nasopharynx. In the soldiers no raise of the carrier rate was observed during the first eight weeks of training. Serological typing revealed that in soldiers type B predominated whereas in students type A was the most frequent one. 22 of the 196 strains belonged to the three types X, Y and Z, recently described bySlaterus (1961). One strain only was non-typable. In spite of the relatively high carrier rates no ease of meningococcal meningitis occurred.

Zusammenfassung

726 Keimträgeruntersuchungen an Soldaten, Studenten und technischen Assistentinnen in einem interepidemischen Zeitraum haben ergeben, daß rund 40% der Soldaten und rund 20% der beiden anderen Personengruppen Meningokokken im Rachen beherbergten. Bei den Soldaten war ein Anstieg der Trägerquote mit der Dauer der Dienstzeit nicht nachzuweisen. Die serologische Typisierung der Stämme zeigte bei den Soldaten ein Überwiegen des Typ B, während bei den Studenten Typ A vorherrschte. 22 der 196 isolierten Stämme gehörten zu den drei vonSlaterus (1961) neu beschriebenen Typen X, Y und Z. Nurein Stamm ließ sich serologisch nicht einordnen. Trotz der relativ hohen Keimträgerquote traten im Beobachtungszeitraum keine Meningokokkenerkrankungen auf.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Literatur

  • Aycock, W. L., andJ. H. Mueller: Meningococcus carrier rates and meningitis incidence. Bact. Rev.14, 115 (1950).

    PubMed  Google Scholar 

  • Berger, U.: Neue Elektivnährböden für Neisseria meningitidis und Neisseria gonorrhoeae. Z. med. Mikrobiol. u. Immunol.152, 169 (1966).

    Google Scholar 

  • -, u. J.Fries: Die Meningokokken-Meningitidis in der Bundesrepublik Deutschland 1945–1965. Arch. Hyg. (Berl.) (im Druck).

  • Branham, S. E.: The significance of serologic types among meningococci. J. Amer. med. Ass.108, 692 (1937).

    Google Scholar 

  • Brown, J. W., andP. K. Condit: Meningococcal infections — Fort Ord and California. Calif. Med.102, 171 (1965).

    PubMed  Google Scholar 

  • Bruns, H., u.J. Hohn: Über den Nachweis und das Vorkommen der Meningokokken im Nasenrachenraum. Klin. Jb.18, 285 (1908).

    Google Scholar 

  • Dudley, S. F., andA. R. Brennan: High and persistent carrier rates of Neisseria meningitidis, unaccompanied by cases of meningitis. J. Hyg. (Lond.)34, 525 (1934).

    Google Scholar 

  • Eastwood, A.: Second report on bacteriological aspects of the meningococcus carrier problem. J. Hyg. (Lond.)17, 63 (1918).

    Google Scholar 

  • —, andF. Griffith: zit. nach D.Nabarro (1917).

    Google Scholar 

  • Felder, J.: Sigmamycin in der Pädiatrie. Schweiz. med. Wschr.88, 953 (1958).

    PubMed  Google Scholar 

  • Gauld, R. L.: Proc. round table on biology of the meningococcus and meningococcal meningitis. 64th Ann. Meet. Amer. Soc. Microbiol., Washington1964, 8.

  • Goeters, W.: Die Meningokokkeninfektionen. Ergebn. Hyg.28, 1 (1954).

    Google Scholar 

  • Glover, J. A.: The cerebro-spinal fever epidemic of 1917 at X depot. J. Hyg. (Lond.)17, 350 (1918a).

    Google Scholar 

  • —: Observations on the meningococcus carrier rate in relation to density of population in sleeping quarters. J. Hyg. (Lond.)17, 367 (1918b).

    Google Scholar 

  • Griffith, F.: Second report on the identification of the meningococcus in the nasopharynx, with special reference to serological reactions. J. Hyg. (Lond.)17, 124 (1918).

    Google Scholar 

  • Gsell, O.: Meningokokkeninfektionen. In: Handb. d. Inn. Medizin, I/1, S. 1369. Berlin, Göttingen, Heidelberg: Springer 1952.

    Google Scholar 

  • Heim, L.: Die antibiotische Behandlung der Meningitis purulenta im Kindesalter. Wien. klin. Wschr.71, 385 (1959).

    PubMed  Google Scholar 

  • Hottinger, A.: Viruserkrankungen im Kindesalter. Dtsch. med. Wschr.87, 2401 (1962).

    PubMed  Google Scholar 

  • Hüther, W., u.M. Kienitz: Studie über das Schicksal meningitiskranker Kinder. Münch. med. Wschr.103, 1097 (1961).

    Google Scholar 

  • Jacobi, G.: Epidemisches und endemisches Aufteten akuter Meningokokkeninfektionen. Z. Kinderheilk.91, 36 (1964).

    Google Scholar 

  • Laybourn, R. L.: A study of epidemic meningitis in Missouri: epidemiological and administrative considerations. Sth. med. J. (Bgham, Ala.)24, 278 (1931).

    Google Scholar 

  • Lingelsheim, W. v.: Die Feststellung der Rachenerkrankung bei der übertragbaren Genickstarre. Klin. Jb.18, 314 (1908).

    Google Scholar 

  • Luz, K.: Das Meningokokkenträgerproblem. Münch. med. Wschr.87, 30 (1940).

    Google Scholar 

  • Millar, J. W.: Round table on biology of the meningococcus and meningococcal meningitis, 64th Ann. Meet. Amer. Soc. Microbiol., Washington1964, 10.

  • Nabarro, D.: Report upon meningococcus-like organisms occurring in the nasopharynx of children, and upon meningococci of spinal origin. Rep. loc. Govt. Bd., N. S.,114, 207 (1917).

    Google Scholar 

  • Peckinpaugh, R. O.: zit. nach N. A.Vedros et al. (1966).

    Google Scholar 

  • Van Peenen, P. F. D., L. E. Sutter, A. D. Mandel, andM. S. Mitchell: Field evaluation of Thayer-Martin medium for identification of meningococcus carriers Amer. J. Epidemiol.82, 329 (1966).

    Google Scholar 

  • Phair, J. J., andE. B. Schoenbach: The dynamics of meningococcal infections and the effect of chemotherapy. Amer. J. Hyg.40, 318 (1944).

    Google Scholar 

  • Ponder, C.: A bacteriological investigation of organisms resembling the meningococcus found by examination of the nasopharynx of persons who had not been in contact with patients suffering from cerebro-spinal fever. J. Hyg. (Lond.)17, 247 (1918).

    Google Scholar 

  • Rake, G.: Studies on meningococcus infection. — VI. The carrier problem. J. exp. Med.59, 553 (1934).

    Google Scholar 

  • Reed, D., J. Brody, B. Huntley andT. Overfield: An epidemic in an Eskimo village due to group-B meningococcus. Part 1. Epidemiology. J. Amer. Med. Ass.196, 383 (1966).

    Google Scholar 

  • Roepstorff, S. O., andE. Hammarström: Diagnosis of asymptomatic meningococcal carriers by a selective medium. Acta path. microbiol. scand.66, 257 (1966).

    PubMed  Google Scholar 

  • Scott, W. M.: A further study of the serological reactions of meningococci from the spinal fluid and the naso-pharynx, with special reference to their classification and to the occurrence of the latter among normal persons. J. Hyg. (Lond.)17, 191 (1918).

    Google Scholar 

  • Slaterus, K. W.: Serological typing of meningococci by means of microprecipitation. Antonie v. Leeuwenhoek27, 305 (1961).

    Google Scholar 

  • —,A. C. Ruys, andI. G. Sieberg: Types of meningococci isolated from carriers and patients in a non-epidemic period in the Netherlands. Antonie v. Leeuwenhoek29, 265 (1963).

    Google Scholar 

  • Stuart, R. D.: Transport medium for specimens in public health bacteriology. Publ. Hlth. Rep. (Wash.)74, 431 (1959).

    Google Scholar 

  • Thayer, J. D., P. F. Frank, andJ. E. Martin: Thayer-Martin selective medium for the cultivation of Neisseria meningitidis from the nasopharynx. Amer. J. Publ. Hlth.55, 923 (1965).

    Google Scholar 

  • —, andJ. E. Martin: A selective medium for the cultivation of N. gonorrhoeae and N. meningitidis. Publ. Hlth Rep. (Wash.)79, 49 (1964).

    Google Scholar 

  • — —: Improved medium selective for cultivation of N. gonorrhoeae and N. meningitidis. Publ. Hlth Rep. (Wash.)81, 559 (1966).

    Google Scholar 

  • Vedros, N. A., P. J. Robinson, andR. R. Gutekunst: Isolation and characterization of a bacterial inhibitor from human throat washings. Proc. Soc. exp. Biol. (N. Y.)122, 249 (1966).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Hygiene-Institut der Universität Heidelberg, Deutschland

    Ulrich Berger

Authors
  1. Ulrich Berger
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Die vorliegenden Untersuchungen wurden mit Unterstützung der Deutschen Forschungsgemeinschaft durchgeführt.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Berger, U. Untersuchungen zur Meningokokkenträgerquote. Z. med. Mikrobiol. u. Immunol. 153, 190–205 (1967). https://doi.org/10.1007/BF02150010

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02150010

Search

Navigation