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Tumour formation in platyfish-swordtail hybrids as a problem of gene regulation

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Zusammenfassung

Bei bestimmten Zahnkarpfen-Bastarden treten stets erbbedingte Melanome auf. Diese entstehen dadurch, dass bestimmte Gene, die für die Differenzierung von Farbzellen verantwortlich sind, enthemmt und gleichzeitig zu einer gesteigerten Aktivität angeregt werden. Die Enthemmung beruht auf einem Verlust bestimmter Repressionsgene und die Aktivitätssteigerung auf einer Einführung polyfaktorieller Systeme von Induktionsgene. Es bestehen schwerwiegende Indizien dafür, dass die Induktorsubstanzen mit Aminosäuren identisch sind.

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  41. I should like to thank Dr.C. Kosswig (Hamburg) and Dr.M. Dzwillo (Hamburg) for their valuable criticism,J. Vielkind (Giessen) for translation, andW. Backer (Giessen) for reading through the manuscript. The experiments of the author have been supported by a grant from Deutsche Forschungsgemeinschaft and Stiftung Volkswagenwerk.

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Authors and Affiliations

  1. Genetisches Institut, Justus-Liebig-Universität, Giessen, Germany

    Fritz Anders

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  1. Fritz Anders
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Additional information

Lecture given at the ‘Internationaler Herbstkongress für Ganzheitsmedizin und Naturheilverfahren 1964’ in Velden/Wörther See (Austria).

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Anders, F. Tumour formation in platyfish-swordtail hybrids as a problem of gene regulation. Experientia 23, 1–10 (1967). https://doi.org/10.1007/BF02142235

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