Summary
The effect of adrenaline on the cellular calcium exchange during the K-depolarization of myocardium was studied in isolated left auricles of guinea-pigs by means of the45Ca. Increasing the extracellular K-concentration from 2.7–30 mM without corresponding reduction in sodium concentration results in a depression of contraction strength of the myocardium when current is applied. The depression is immediately reversible by using adrenaline. This was associated with a significant increase of the45Ca exchange.
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Prignitz, R. Der Einfluss von Adrenalin auf das Verhalten des zellulären Kalziums während der K-Depolarisation des Herzmuskels von Meerschweinchen. Experientia 24, 913–914 (1968). https://doi.org/10.1007/BF02138650
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DOI: https://doi.org/10.1007/BF02138650