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Rat mammary cancer inhibition by a prolactin suppressor, 2-bromo-α-ergokryptine (CB 154)

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  • Pharmacologia
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Zusammenfassung

2-Br-α-Ergokryptin (=CB 154) wurde täglich während 80–100 Tagen, beginnend mit der Carcinogenapplikation, DMBA - (5 mg i.v.)-behandelten weiblichen Ratten in der Dosis 6 mg/kg i.p. verabreicht. CB 154 bewirkte ein verzögertes Erscheinen und ein langsameres Wachsen der Mamma-Tumoren sowie eine verminderte Todesrate der carcinogenbehandelten Ratten.

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Authors and Affiliations

  1. Biological and Medical Research Division, Sandoz Ltd., CH-4002, Basel, Switzerland

    H. Stähelin, B. Burckhardt-Vischer & E. Flückiger

Authors
  1. H. Stähelin
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  2. B. Burckhardt-Vischer
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  3. E. Flückiger
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Stähelin, H., Burckhardt-Vischer, B. & Flückiger, E. Rat mammary cancer inhibition by a prolactin suppressor, 2-bromo-α-ergokryptine (CB 154). Experientia 27, 915–916 (1971). https://doi.org/10.1007/BF02135741

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  • DOI: https://doi.org/10.1007/BF02135741

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