Skip to main content
Log in

Thiamine transport by human intestine in vitro

  • Published:
Experientia Aims and scope Submit manuscript

Summary

Surgical specimens of human gastrointestinal mucosa and muscle were incubated in vitro with thiaminethiazole-2-14C. Labelled thiamine uptake was uphill in mucosal tissues and downhill in muscle. Small intestinal mucosa accumulated labelled thiamine in a phosphorylated form, while gastric and colonic mucosa, as well as muscular layers of all gastrointestinal segments studied, did not.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. A. C. Da Silva and A. C. Ivy, Am. J. Physiol.201, 185 (1961).

    Article  Google Scholar 

  2. A. C. Da Silva, M. G. Vecchia, R. N. Rogano and R. C. De Angelis, 23rd, Int. Cong. Physiol. Sci. Tokyo 1965, p. 220.

  3. U. Ventura, E. Giacalone and G. Rindi, Boll. Soc. ital. Biol. sper.39, 1443 (1963).

    CAS  PubMed  Google Scholar 

  4. B. Gassmann, J. Proll and D. Lexow, Int. Z. Vitaminforsch.37, 203 (1967).

    CAS  PubMed  Google Scholar 

  5. E. Sandner and B. Gassmann, Nahrung11, 583 (1967).

    Article  CAS  Google Scholar 

  6. G. Sciorelli and U. Ventura, Acta vitamin enzym.23, 231 (1969).

    CAS  Google Scholar 

  7. D. Polin, E. R. Wynosky and C. C. Porter, Fed. Proc.21, 261 (1962).

    Google Scholar 

  8. D. Polin, E. R. Wynosky and C. C. Porter, Poult. Sci.42, 1057 (1963).

    Article  Google Scholar 

  9. K. R. Fox and C. A. M. Hogben, Fed. Proc.26, 502 (1967).

    Google Scholar 

  10. U. Ventura and G. Rindi, Experientia21, 645 (1965).

    Article  CAS  PubMed  Google Scholar 

  11. T. Komai, K. Kawai and H. Shindo, J. Nutr. Sci. Vitamin.20, 163 (1974).

    Article  CAS  Google Scholar 

  12. T. Komai and H. Shindo, J. Nutr. Sci. Vitamin.20, 179 (1974).

    Article  CAS  Google Scholar 

  13. A. M. Hoyumpa, H. M. Middleton, F. A. Wilson and S. Schenker, Gastroenterology68, 1218 (1975).

    Article  CAS  PubMed  Google Scholar 

  14. K. Schaller and H. Höller, Int. J. Vit. Nutr. Res.44 443 (1974).

    CAS  Google Scholar 

  15. G. Rindi and U. Ventura, Physiol. Rev.52, 821 (1972).

    Article  CAS  PubMed  Google Scholar 

  16. A. S. Schultz, R. F. Light and C. N. Frey, Proc. Soc. exp. Biol. Med.38, 404 (1938).

    Article  Google Scholar 

  17. B. Alexander, G. Landwehr and F. Mitchell, J. clin. Invest.25, 294 (1946).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  18. T. E. Friedemann, T. C. Kmieciak, P. K. Keegan and B. B. Sheft, Gastroenterology11, 100 (1948).

    CAS  PubMed  Google Scholar 

  19. A. B. Morrison and J. A. Campbell, J. Nutr.72, 435 (1960).

    Article  CAS  PubMed  Google Scholar 

  20. A. D. Thomson, H. Baker and C. M. Leevy, J. Lab. Clin. Med.76, 34 (1970).

    CAS  PubMed  Google Scholar 

  21. A. D. Thomson and C. M. Leevy, Clin. Sci.43, 153 (1972).

    Article  CAS  PubMed  Google Scholar 

  22. G. Levy and R. R. Hewitt, Am. J. Clin. Nutr.24, 401 (1971).

    Article  CAS  PubMed  Google Scholar 

  23. H. A. Krebs and K. Henseleit, Hoppe-Seylers Z. physiol. Chem.210, 33 (1932).

    Article  CAS  Google Scholar 

  24. R. K. Crane and P. Mandelstam, Biochim. biophys. Acta, Amst.45, 460 (1960).

    Article  CAS  Google Scholar 

  25. G. Rindi and U. Ventura, Experientia23, 175 (1967).

    Article  CAS  PubMed  Google Scholar 

  26. S. K. Sharma and J. H. Quastel, Biochem. J.94, 790 (1965).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  27. H. B. Burch, O. A. Bessey, R. H. Love and O. H. Lowry, J. biol. Chem.198, 477 (1952).

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

This work was supported in part by a grant from the Italian Research Council, Rome, Italy.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Rindi, G., Ferrari, G. Thiamine transport by human intestine in vitro. Experientia 33, 211–213 (1977). https://doi.org/10.1007/BF02124072

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02124072

Keywords

Navigation