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Resolution of Ca++-ATPase of sarcoplasmic reticulum into subunits

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Summary

The Ca++-ATPase system of sarcoplasmic reticulum (SR) was resolved into several subunits by isoelectric focusing and isotachophoresis in acrylamide gels. The results obtained support the concept that the ATPase system of SR is oligomeric forming a tetramer of 100,000 mol.wt subunits.

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Acknowledgments. We are grateful to Prof. A. P. Carvalho for interesting discussions. We are indebted to Mr Jasmim António for typing the manuscript. This research was supported by I. A. C., grant CB/2.

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Madeira, M.C., Antunes-Madeira, M.C. Resolution of Ca++-ATPase of sarcoplasmic reticulum into subunits. Experientia 33, 188–190 (1977). https://doi.org/10.1007/BF02124058

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