Summary
The action of angiotensin II on cardiac uptake of norepinephrine was investigated in the rat in vivo and in vitro. In contrast to desipramine, neither infusion of subpressive (10 ng/kg/min) or pressive (50–150 ng/kg/min) amounts of angiotensin on intact and/or binephrectomized rats, nor incubation of cardiac slices with angiotensin II (10−5; 10−9 M) impair the accumulation of tritiated norepinephrine and the level of metabolites. It is thus concluded that there is no inhibiting action of angiotensin II on the cardiac uptake of norepinephrine.
Similar content being viewed by others
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Chevillard, C., Alexandre, J. Action, in vitro et in vivo, de l'angiotensine II sur le captage cardiaque de la noradrénaline. Experientia 26, 1334–1336 (1970). https://doi.org/10.1007/BF02113014
Published:
Issue Date:
DOI: https://doi.org/10.1007/BF02113014