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Morphology of the spleen in women who died of metastatic genital tract cancer

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Summary

The histology of the white pulp of the spleen was assessed in 56 women who died of metastatic genital tract cancer and in 56 age-matched women who died of a myocardial infarction or a stroke. Special attention was paid to the areas associated with T cells and B cells.

The T-cell and B-cell areas were profoundly depleted in patients with carcinoma. This suggests that women who die of genital tract cancer have impaired humoral and cell-mediated immunity.

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  1. Department of Pathology, University of Kuopio, POB 138, 70101, Kuopio 10, Finland

    Kari J. Syrjänen

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Syrjänen, K.J. Morphology of the spleen in women who died of metastatic genital tract cancer. Arch. Gynecol. 230, 33–40 (1980). https://doi.org/10.1007/BF02108596

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  • DOI: https://doi.org/10.1007/BF02108596

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