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Kontrollmethoden zum Nachweis der Tuberkulostatica zweiter Ordnung im Urin

Methods for checking the presence of second line antituberculous drugs in the urine

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Beiträge zur Klinik und Erforschung der Tuberkulose und der Lungenkrankheiten Aims and scope Submit manuscript

Summary

Patients undergoing prolonged treatment are often showing a tendency to take their drugs irregularly. While we have a number of tests available for checking the ingestion of primary antituberculous drugs little effort has been made so far to develop procedures for the detection of secondary antituberculous agents in the urine. This treatise deals with control tests to detect pyrazinamide, cycloserine and ethionamide in urine and discusses the merit of these methods.

Zusammenfassung

Patienten unter Dauerbehandlung zeigen oft eine Tendenz, die Arzneimittel unregelmäßig einzunehmen. Während wir eine reiche Auswahl von Testen besitzen zur Nachprüfung der Einnahme der Tuberkulostatica erster Ordnung, hat man für den Nachweis der zweitreihigen Antituberkulotica im Harn nur wenig Interesse gezeigt. Diese Abhandlung beschreibt Kontrollteste zum Nachweis von Pyrazinamid, Cycloserin und Äthionamid und bespricht die Ergebnisse dieser Methoden.

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Authors and Affiliations

  1. Dept. of National Health & Welfare, National Reference Centre for Tuberculosis Laboratory of Hygiene, Ottawa, Canada

    L. Eidus

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Eidus, L. Kontrollmethoden zum Nachweis der Tuberkulostatica zweiter Ordnung im Urin. Beitr. Klin. Tuberk. 137, 196–203 (1968). https://doi.org/10.1007/BF02097996

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  • DOI: https://doi.org/10.1007/BF02097996

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