Abstract
Deproteinized uraemic sera or their nonprotein fractions inhibit glucose utilization by the rat diaphragm. Inhibitory activity of the uraemic sera on glucose utilization is caused by at least two substances, which differ in their mobility on a column of Sephadex G-25. The nature of these substances remains obscure.
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Cohen, B. D.: Abnormal carbohydrate metabolism in uraemia.Ann. Int. Med. 57, 204 (1962).
Dzúrik, R., Krajči-Lazáry, B.: Metabolizmus glycidov u pacientov v renálnej insuficienciiLek. Obzor, 17, 265 (1968).
Dzúrik, R., Krajči-Lazáry, B.: The effect of uremic serum on carbohydrate metabolism in rat diaphragm.Experientia, 24, 552 (1968).
Dzúrik, R., Niederland, T. R., Černáček, P.: Abnormal carbohydrate metabolism in liver slices incubated in uraemic sera.Clin. Sci., 37, 409 (1969).
Dzúrik, R., Valovičová, E.: Glucose utilization in muscle during uremia; in vitro study.Clin. Chim. Acta, 30, 137 (1970).
Heintz, R., Renner, D.: Über Hemmwirkungen des Serums von Kranken mit hepatorenalem Syndrom und mit chronischer Urämie auf Sauerstoffverbrauch und Kohlenhydratoffwechsel von Nieren-und Hirngewebe der Ratte.Klin. Wschr., 43, 1167 (1965).
Morgan, J. M.: Study of the effect of uremic metabolites on erythrocyte glycolysis.Metabolism 13, 629 (1964).
Neubauer, E.: Über Hyperglykämie bei Hochdrucknephritis und die Beziehungen zwischen Glykämie und Glukosurie beim Diabetes mellitus.Biochem. Z., 25, 284 (1910).
Samaan, N. A., Freeman, R. M.: Growth hormone levels in severe renal failure.Metabolism 19, 102 (1970).
Teuscher, A.: Beurteilung der Blutzuckerwerte und der Glukosetoleranz bei Urämie.Schweiz. Med. Wschr., 94, 69 (1964).
Westervelt, B. F. Jr., Schreiner, G. E.: The carbohydrate intolerance of uremic patients.Ann. Int. Med., 57, 266 (1962).
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Dzúrik, R., Hupková, V., Holomáň, J. et al. Abnormal carbohydrate metabolism in uraemia. International Urology and Nephrology 3, 409–413 (1971). https://doi.org/10.1007/BF02082290
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DOI: https://doi.org/10.1007/BF02082290