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Histologic abnormalities of the left ventricle in a patient with arrhythmogenic right ventricular dysplasia

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Summary

Right ventricular histologic abnormalities have been described in association with arrhythmogenic right ventricular dysplasia, but the cause of the disease is unknown. Identical abnormalities were noted in endomyocardial biopsy specimens from the right and left ventricles of a 20-year-old male patient with the clinical syndrome of arrhythmogenic right ventricular dysplasia. Left ventricular function was normal at rest and during bicycle exercise. Eighteen months previously, he had shown clinical and serologic evidence of mycoplasmal myocarditis. Arrhythmogenic right ventricular dysplasia may represent predominant involvement of the right ventricle in a generalized cardiomyopathic process, possibly as a consequence of healed myocarditis.

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References

  1. Fontaine G, Guiraudon G, Frank R, Vedel J, Grosgogeat Y, Cabrol C, Facquet J (1977) Stimulation studies and epicardial mapping in ventricular tachycardia: Study of mechanisms and selection for surgery. In: Kulbertus HE (ed) Re-entrant arrhythmias: Mechanisms and treatment. University Park Press, Baltimore, pp 334–350

    Google Scholar 

  2. Marcus FI, Fontaine GH, Guiraudon G, Frank R, Laurenceau JL, Malergue C, Grosgogeat Y (1982) Right ventricular dysplasia: A report of 24 adult cases. Circulation 65: 384–398

    PubMed  Google Scholar 

  3. Reiter MJ, Smith WM, Gallagher JJ (1983) Clinical spectrum of ventricular tachycardia with left bundle branch morphology. Am J Cardiol 51: 113–121

    PubMed  Google Scholar 

  4. Pietras RJ, Lam W, Bauernfeind R, Sheikh A, Palileo E, Strasberg B, Swiryn S, Rosen KM (1983) Chronic recurrent right ventricular tachycardia in patients without ischemic heart disease: Clinical, hemodynamic, and angiographic findings. Am Heart J 105: 357–366

    PubMed  Google Scholar 

  5. Rowland R, McKenna WJ, Sugrue D, Barclay R, Foale RA, Krikler DM (1984) Clinical and electrophysiological features of ventricular tachycardia of left bundle branch block configuration in patients with isolated right ventricular dilatation. Br Heart J 51: 15–24

    PubMed  Google Scholar 

  6. Manyari DE, Klein GJ, Gulamhusein S, Boughner D, Guiraudon GM, Wyse G, Mitchell LB, Kostuk WJ (1983) Arrhythmogenic right ventricular dysplasia: A generalized cardiomyopathy? Circulation 68: 251–257

    PubMed  Google Scholar 

  7. Guiraudon GM, Klein GJ, Gulamhusein SS, Painvin GA, Del Campo C, Gonzales JC, Ko PT (1983) Total disconnection of the right ventricular free wall: Surgical treatment of right ventricular tachycardia associated with right ventricular dysplasia. Circulation 67: 463–470

    PubMed  Google Scholar 

  8. Hammill SC, Holmes DR Jr, Wood DL, Osborn MJ, McLaran C, Sugrue DD, Gersh BJ (1984) Electrophysiologic testing in the upright position: Improved evaluation of patients with rhythm disturbances using a tilt table. J Am Coll Cardiol 4: 65–71

    PubMed  Google Scholar 

  9. Nippoldt TB, Edwards WD, Holmes DR Jr, Reeder GS, Hartzler GO, Smith HC (1982) Right ventricular endomyocardial biopsy: Clinicopathologic correlates in 100 consecutive patients. Mayo Clin Proc 57: 407–418

    PubMed  Google Scholar 

  10. Edwards WD, Holmes DR Jr, Reeder GS (1982) Diagnosis of active lymphocytic myocarditis by endomyocardial biopsy: Quantitative criteria for light microscopy. Mayo Clin Proc 57: 419–425

    PubMed  Google Scholar 

  11. Viola AR, Adaro FVM, Roncoroni AJ (1970) Idiopathic myocardiopathy resulting in failure of contractility of the right ventricle. Am J Med 48: 235–238

    PubMed  Google Scholar 

  12. Vecht RJ, Carmichael DJS, Gopal R, Philip G (1979) Uhl's anomaly. Br Heart J 41: 676–682

    PubMed  Google Scholar 

  13. Fitchett DH, Sugrue DD, MacArthur CG, Oakley CM (1984) Right ventricular dilated cardiomyopathy. Br Heart J 51: 25–29

    PubMed  Google Scholar 

  14. Lewes D, Rainford DJ, Lane WF (1974) Symptomless myocarditis and myalgia in viral and myoplasma pneumonia infections. Br Heart J 36: 924–932

    PubMed  Google Scholar 

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Sugrue, D.D., Edwards, W.D. & Olney, B.A. Histologic abnormalities of the left ventricle in a patient with arrhythmogenic right ventricular dysplasia. Heart Vessels 1, 179–181 (1985). https://doi.org/10.1007/BF02066415

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