Abstract
Mg, Sr and F ions acted as inhibitors of apatite formation when added to a calcification buffer separately or in combinations.
The precipitation of apatite under the influence of apatite seeds was less susceptible to inhibition than were spontaneous nucleation and apatite formation catalyzed by sheep bone collagen, while the latter two were about equally susceptible. Combinations of Mg with Sr or F ions showed additive effects.
These results suggest that no specific effects of these inhibitors occurred on the catalytic action of the bone collagen different from their effects on the nucleation of apatite as such.
Résumé
Des ions de Mg, Sr et F sont inhibitoires pour la formation de l'apatite quand on les ajoute à un tampon de calcification, séparément ou en combinaisons.
La précipitation de l'apatite causée par des cristaux d'apatite est moins sensible à l'action inhibitrice que la nucléation spontanée et que la précipitation catalysée par la collagène d'os de mouton. La précipitation spontanée ou catalysée sont approximativement aussi sensibles. L'inhibition par des combinaisons de Mg avec des ions de Sr ou de F est additive.
Ces résultats montrent que ces inhibiteurs ont acucune action spécifique sur la catalysation par la collagène de l'os de mouton qui soit différente de celle sur la nucléation de l'apatite en soi.
Zusammenfassung
Mg, Sr und F Ionen hemmten die Fällung von Apatit wenn sie zu einem Calciumphosphatpuffer einzeln oder zusammen hinzugefügt wurden.
Die Fällung von Apatit durch Apatitkeime war weniger empfindlich hinsichtlich der Hemmung als die spontane Nucleation und als die Fällung von Apatit, welche von Schafsknochenkollagen katalysiert werden kann. Die spontane und katalysierte Fällung sind ungefähr gleich empfindlich. Die Hemmung von Mg in Kombination mit Sr oder F Ionen war additiv.
Diese Resultate weisen darauf hin, daß keine spezifischen Effekte bei der Katalyse von Knochenkollagen vorliegen, welche von den Effekten bei der Nucleation von Apatit an sich verschieden sind.
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Bachra, B.N., Fischer, H.R.A. The effect of some inhibitors on the nucleation and crystal growth of apatite. Calc. Tis Res. 3, 348–357 (1969). https://doi.org/10.1007/BF02058677
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DOI: https://doi.org/10.1007/BF02058677