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Influence of fungicides on mycotoxin production by Alternaria mali

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Abstract

Extracts of fungicide induced variants ofAlternaria mali were tested with mice and bacteria. Both the living fungi and their crude chloroform extracts inhibited growth ofStaphylococcus aureaus, Sarcina lutea, Bacillus mycoides, andB. subtilis. B. megaterium was not sensitive to most of the extracts and was only slightly so to the remainder. The LD50 in mice when injected intraperitoneally ranged from 300 mg/kg to 2400 mg/kg; however, in some cases there were no lethal effects. The toxicity of the wild type was greatly reduced when grown in the presence of fungicide decomposition products. Altenuene, alternariol, and alternariol monomethyl ether were not found in any of the extracts.

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References

  • Cole, H., Taylor, B., &Duich, J. (1968). Evidence of differing tolerances to fungicides among isolates ofSclerotinia homoeocarpa.Phytopathol. 58683–686.

    Google Scholar 

  • Elsaid, H. M. &Sinclair, J. B. (1963). Adapted tolerance to organic fungicides by isolates ofRhizoctonia solani from seedling corn.Phytopathol. 54:518–522.

    Google Scholar 

  • Parry, K. E. &Wood, R. K. S. (1958) The adaptation of fungi to fungicides: Adaptation to copper and mercury salts.Ann. Appl. Biol. 46:456.

    Google Scholar 

  • Partridge, A. D. &Rich, A. E. (1962) Induced tolerance to fungicides in three species of fungi.Phytopathol. 52:1000–1004.

    Google Scholar 

  • Pero, R. W., Owens, R. G., &Harvan, D. (1971) Gas and thin-layer chromatographic methods for analysis of the mycotoxins altenuene, alternariol, and alternario monomethyl ether.Anal. Biochem. 43:80–88.

    Google Scholar 

  • Prasad, I. P. &Pramer, D. (1968) Genetic effects of ferbam onAspergillus niger andAllium cepa.Phytopathol. 58:1188–1189.

    Google Scholar 

  • Raper, K. B. &Thom, C. (1949) A manual of the Penicillia. p. 75. The Williams and Wilkins Co., Baltimore, Md.

    Google Scholar 

  • Siebert, D., Zimmermann, K. &Lemperle E. (1970) Genetic effect of fungicides.Mutation Res. 10:533–543.

    Google Scholar 

  • Slifkin, M. K. (1972) Apparent induction of mutants and enhancement of conidial formation by fungicides inAlternaria mali. Mycopath. & Mycol. Appl. (in press).

  • Slifkin, M. K. &Spalding, J. (1970) Studies of the toxicity ofAlternaria mali.Toxicol. Appl. Pharmacol. 17:375–386.

    Google Scholar 

  • Webster, R. K., Ogawa, J. M., &Moore, C. J. (1968) The occurrence and behavior of variants of Rhizopus stolonifer tolerant to 2,6 dichloro-4-nitroaniline.Phytopathol. 58:997–1003.

    Google Scholar 

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Authors and Affiliations

  1. National Institute of Environmental Health Sciences, P. O. Box 12233, 27709, Research Triangle Park, North Carolina

    Hayes Brown

Authors
  1. Miriam K. Slifkin
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  2. Anna Ottolenghi
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  3. Hayes Brown
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Slifkin, M.K., Ottolenghi, A. & Brown, H. Influence of fungicides on mycotoxin production by Alternaria mali. Mycopathologia et Mycologia Applicata 50, 241–248 (1973). https://doi.org/10.1007/BF02053373

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  • DOI: https://doi.org/10.1007/BF02053373

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