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Heterozygous diploid strains of Aspergillus nidulans: Enhanced virulence for mice in comparison to a prototrophic haploid strain

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Abstract

The paper describes quantitative studies of the virulence for DBA/2J mice of three heterozygous diploid strains ofAspergillus nidulans synthesized from avirulent auxotrophic haploid strains, and auxotrophic strains of reduced virulence. These studies demonstrate that the heterozygous diploid strains possess an unusually high virulence for mice in comparison to a haploid prototrophic strain ofA. nidulans employed as a virulence standard.

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Authors and Affiliations

  1. Department of Pathology, College of Medicine, The Pennsylvania State University Milton S. Hershey Medical Center Hershey, 17033, Pennsylvania

    Dallas M. Purnell

  2. Department of Pathology, University of Washington Seattle, 98105, Washington

    George M. Martin

Authors
  1. Dallas M. Purnell
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  2. George M. Martin
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Purnell, D.M., Martin, G.M. Heterozygous diploid strains of Aspergillus nidulans: Enhanced virulence for mice in comparison to a prototrophic haploid strain. Mycopathologia et Mycologia Applicata 49, 307–319 (1973). https://doi.org/10.1007/BF02050724

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  • DOI: https://doi.org/10.1007/BF02050724

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