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Étude cinétique de l'hypersensibilité de type retardé dans la candidose expérimentale de la souris

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Abstract

Mice were inoculated with different quantities of blastospores ofCandida albicans by subcutaneous or intravenous ways. Delayed hypersensitivity was then studied during the course of infection by means of the inhibition of macrophage spreading test. In the same time retrocultures were done from kidney material, target organs in the experimental candidiasis. The results obtained in this way enabled the authors to think that cellular immunity plays a role in this experimental model as described by Mackaness.

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Authors and Affiliations

  1. Parasitologie Dépt. Biologie appliquée I.U.T.-Cité Scientifique Sac Postal no 5, 59650, Villeneuve D'Ascq, France

    F. E. Floc'h

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  1. F. E. Floc'h
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  2. J. Biguet
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  3. S. Andrieu
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  4. A. Vernes
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collaboration technique de Madame R. Popeye & Monsieur J. LeClercq

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Travail de l'Unité 42 de l'INSERM et du Groupe de Mycologie Fondamentale et Appliquée de LILLE.

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Floc'h, F.E., Biguet, J., Andrieu, S. et al. Étude cinétique de l'hypersensibilité de type retardé dans la candidose expérimentale de la souris. Mycopathologia et Mycologia Applicata 54, 475–483 (1974). https://doi.org/10.1007/BF02050053

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  • DOI: https://doi.org/10.1007/BF02050053

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