Abstract
PURPOSE: The postoperative course of intestinal Behçet's disease was studied in nine patients who had undergone a total of 15 operations due to intestinal ulcers. METHODS: These patients were followed up for an average of 6.0 years (range, 1 year, 3 months to 13 years, 10 months) after each operation and they were repeatedly examined by double-contrast radiography and/or colonofiberscopy. RESULTS: Recurrence of intestinal ulcers was observed in 12 (80 percent) of the 15 surgical cases. The incidence (50 percent) of postoperative recurrence in six cases in which intraoperative endoscopy revealed no abnormality in the retained intestine was lower than that (100 percent) in nine cases without this examination. Recurrent intestinal lesions in most cases were demonstrated as multiple aphthoid ulcers in the ileum near the ileocolectomy, or as one or two deep ulcers at the ileocolectomy site. The recurrent ulcers were successfully treated by various medical therapies, but the effectiveness of these therapies was only temporary. CONCLUSION: In the case of this disease, intraoperative endoscopy may be useful for preventing postoperative recurrence and periodic follow-up examination with radiography and endoscopy should be performed, even after surgery.
Similar content being viewed by others
References
Behçet H. Über rezidivierende aphthöse, durch ein Virus Verursachte Geschwüre am Mund, am Auge und an den Genitalien. Dermatol Wschr 1937;105:1152–7.
Shimizu T, Ehrlich GE, Inaba G, Hayashi K. Behçet disease (Behçet syndrome). Semin Arthritis Rheumatol 1979;8:223–60.
Baba S, Maruta M, Ando K, Teramoto T, Endo I. Intestinal Behçet's disease: report of five cases. Dis Colon Rectum 1976;19:428–40.
Kasahara Y, Tanaka S, Nishino M, Umemura H, Shiraha S, Kuyama T. Intestinal involvement in Behçet's disease: review of 136 surgical cases in the Japanese literature. Dis Colon Rectum 1981;24:103–6.
Hanauer SB, Kraft SC. Gastrointestinal manifestations of the vasculitis syndromes. In: Berk JE, ed. Bockus gastroenterology. 4th ed. Philadelphia: WB Saunders, 1985:4525–44.
Iida M, Suekane H, Tada S, et al. Double-contrast radiographic features in primary small intestinal lymphoma of the ‘Western’ type: correlation with pathological findings. Clin Radiol 1991;44:322–6.
Mizushima Y, Inaba G, Mimura Y, Ono S. Diagnostic criteria for Behçet's disease in 1987 and guidelines for treating Behçet's disease. Saishin Igaku 1988;43:382–91.
Iida M, Yao T, Ohsato K, Itoh H, Watanabe H. Diagnostic value of intraoperative fiberscopy for small-intestinal polyps in familial adenomatosis coli. Endoscopy 1980;12:161–5.
Kuroki F, Iida M, Matsui T, Matsumoto T, Fujishima M, Yao T. Intraoperative endoscopy for small intestinal damage in radiation enteritis. Gastrointest Endosc 1992;38:196–7.
Baba S. Clinical studies on intestinal Behçet disease. Stomach Intestine 1979;14:885–92.
Ketch LL, Buerk CA, Liechty RD. Surgical implications of Behçet's disease. Arch Surg 1980;115:759–60.
Author information
Authors and Affiliations
About this article
Cite this article
Iida, M., Kobayashi, H., Matsumoto, T. et al. Postoperative recurrence in patients with intestinal Behçet's disease. Dis Colon Rectum 37, 16–21 (1994). https://doi.org/10.1007/BF02047208
Issue Date:
DOI: https://doi.org/10.1007/BF02047208