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Effects of antibacterial drugs on European eal (Anguilla anguilla L., 1758) peripheral leucocytes

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Abstract

In two experiments with European eel (Anguilla anguilla L., 1758) the effects of flumequine (FQ), oxytetracycline (OTC) and furazolidone (FZ) on peripheral blood leucocytes were tested using measurements of differential white blood cell counts in blood smears, flow cytometry and respiratory burst activity of adherent cells. Results revealed that FQ and OTC affected (different) leucocyte populations, whereas no effect of FZ was detected in these experiments. These effects should be taken into account when drugs are registered for official approval in veterinary (fish) medicine.

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Authors and Affiliations

  1. Department of Fish Culture and Fisheries, Wageningen Agriculture University, PO Box 338, 6700 AH, Wageningen, The Netherlands

    J. H. Boon, M. H. T. van der Heijden & M. W. T. Tanck

  2. Department of Cell Biology and Animal Morphology, Wageningen Agriculture University, PO Box 338, 6700 AH, Wageningen, The Netherlands

    B. M. L. Verburg-Van Kemenade & J. H. W. M. Rombout

Authors
  1. J. H. Boon
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  2. M. H. T. van der Heijden
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  3. M. W. T. Tanck
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  4. B. M. L. Verburg-Van Kemenade
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  5. J. H. W. M. Rombout
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Boon, J.H., van der Heijden, M.H.T., Tanck, M.W.T. et al. Effects of antibacterial drugs on European eal (Anguilla anguilla L., 1758) peripheral leucocytes. Comparative Haematology International 5, 268–272 (1995). https://doi.org/10.1007/BF02044144

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