Skip to main content
SpringerLink
Log in

Evaluation of asymmetries of blood flow rate and of circulation time by intravenous radionuclide cerebral angiography in patients with ischemic completed stroke

  • Original Articles
  • Published:
The Italian Journal of Neurological Sciences Aims and scope Submit manuscript

Abstract

155 patients with ischemic completed stroke of varying severity and outcome have been evaluated by radionuclide cerebral angiography with analysis of regional time-activity curves.

Two parameters have been evaluated: area under the upslope of the curve (A up)reflecting regional blood flow rate and moment of the whole curve reflecting tracer circulation time (rABCT)

Combination of these two methods ensured increased detection of perfusion asymmetries.

Sommario

155 pazienti con “completed stroke” di origine ischemica, di varia gravità ed esiti, sono stati studiati con angioscintigrafia cerebrale endovenosa e analisi delle curve regionali attività-tempo.

Sono stati valutati due parametri: l'uno, area sottesa dalla parte ascendente della curva (A up),correlato con il flusso ematico, l'altro, momento normalizzato della curva (rABCT), correlato col tempo di circolazione regionale.

La combinazione dei due metodi permette una maggiore accuratezza diagnostica rispetto a quella dei due singoli approcci e permette valutazioni fisiopatologiche in termini di flusso, tempo di transito e volume vascolare.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Ames A. III,Wright R.L., Kowada M., Turston J.M., Majno G.:Cerebral Ischemia-II The no-reflow phenomenon. Am. J. Pathol., 52, 437–453, 1968

    PubMed  Google Scholar 

  2. Bartolini A.:Regional Arm-Brain mean transit time in the diagnostic evaluation of patients with cerebral vascular disease. Stroke, 12, 241–245, 1981

    PubMed  CAS  Google Scholar 

  3. Bartolini A.:Relationship between perfusion defects and static brain scan positivity in patients with completed stroke: considerations about the origin of the increased uptake. J. Neurol. Neurosurg. Psychiat., 45, 102–106, 1982

    PubMed  CAS  Google Scholar 

  4. Bartolini A., Primavera A.:Influence of cardiac factors on the regional Arm-Brain mean transit time. J. Nucl. Med. All. Sci., 26, 93–88, 1982

    Google Scholar 

  5. Cronqvist S., Laroche F.:Transient hyperhaemia in focal cerebral vascular lesions studied by angiography and regional cerebral blood flow measurements. Br. J. Radiol., 40, 270–274, 1976

    Google Scholar 

  6. Di Chiro G., Timins L., Jones A.E., Johnston G.S., Hammock M.K., Swann S.:Radionuclide scanning and microangiography in evolving and completed brain infarction. Neurology 24, 418–423, 1974

    PubMed  Google Scholar 

  7. Fieschi C., Bozzao L.:Transient embolic occlusion of the middle cerebral and carotid arteries in cerebral apoplexy. J. Neurol. Neurosurg. Psychiat., 32, 236–240, 1969

    Article  PubMed  CAS  Google Scholar 

  8. Grubb R.J., Raichle M.E., Eichling J.O.:The effect of changes of PaCO 2,on cerebral blood volume, blood flow and vascular mean transit time. Stroke, 5, 630–639, 1974

    PubMed  Google Scholar 

  9. Hoedt Rasmussen K., Skinhoi J.E., Paulson O., Ewald J., Bjerrum J.K., Fahrenkrug A., Lassen N.A.:Regional cerebral blood flow in acute apoplexy: the luxury perfusion syndrome of the brain tissue. Arch. Neurol., 17, 271–281, 1967

    PubMed  CAS  Google Scholar 

  10. Lassen N. A.:The luxury perfusion syndrome and its possible relation to the acute metabolic acidosis localized within the brain. Lancet 2, 1113–1115, 1966

    PubMed  CAS  Google Scholar 

  11. Lavy S., Melamed E., Portnoy Z.:The effect of cerebral infarction on regional blood flow of the contralateral hemisphere. Stroke 6, 160–163, 1975

    PubMed  CAS  Google Scholar 

  12. McKay W.G., Andrews J.T., Mathur K.S.:Vascular cerebral infarction demonstrated by serial gamma camera scintiphotography. Brit. J. Radiol., 49, 600–603, 1976

    Article  PubMed  CAS  Google Scholar 

  13. Meyer J.S., Shinoara Y., Kanda T., Fukuchi Y., Ericsson A., Gdo K.N.:Diaschisis resulting from acute unilateral cerebral infarction—quantitative evidence for man. Arch. Neurol., 23, 241–247, 1970

    PubMed  CAS  Google Scholar 

  14. Moses D.C., Natarajan T.K., Previosi T.J., Udvardhely G.B., Wagner H.N., Jr.:Quantitative cerebral circulation studies with sodium Pertechnetate. J. Nucl. Med., 14, 142–148, 1973

    PubMed  CAS  Google Scholar 

  15. Paulson O.B.:Cerebral apoplexy (Stroke): pathogenesis, pathophysiology and therapy as illustrated by regional blood flow measurements in brain Stroke. 2, 327–360, 1971

    PubMed  CAS  Google Scholar 

  16. Weissman B.N., Holman L.B., Rosenbaum A.E.:Radioactive angiography in graded carotid stenosis. Radiology, 115, 339–342, 1975

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Clinica Neurologica dell'Università, Genova

    Bartolini A. & Primavera A.

  2. Centro Neurofisiologia CNR Genova, Italia

    Gasparetto B.

Authors
  1. Bartolini A.
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Primavera A.
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Gasparetto B.
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Lavoro eseguito col contributo del CNR

Rights and permissions

Reprints and permissions

About this article

Cite this article

Bartolini, A., Primavera, A. & Gasparetto, B. Evaluation of asymmetries of blood flow rate and of circulation time by intravenous radionuclide cerebral angiography in patients with ischemic completed stroke. Ital J Neuro Sci 5, 433–436 (1984). https://doi.org/10.1007/BF02042628

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02042628

Key-words

Search

Navigation