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Effect of copper(II) ions on the stability of spin adducts formed by the reaction of 5,5-dimethylpyrroline-N-oxide with hydroxyl and hydroxylalkyl radicals

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Abstract

The reactions of copper(II) species with spin adducts formed by reaction of OH·, CH3CHOH or (CH3)2COH with DMPO (5,5-dimethylpyrroline-N-oxide) have been investigated. The spin adducts prepared by γ-irradiation of appropriate solutions were detected using esr. Copper(II) in the form of aqua, phen, or 1-alanine complexes reacted rapidly with the OH· adduct to give products that gave no esr signal, but with the hydroxylalkyl adducts, reacted to give a new 9-line esr signal, identified as due to the H· adduct, (DMPO-H·). Measurement of the yield of Cu(phen) +2 formed by reaction of the copper(II) complex with the spin adduct showed that approximately 25% of the radiation-produced radicals formed esr detectable spin adducts. The implications of these findings for the use of spin trapping to detect radical intermediates in biological systems is discussed.

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  1. Radiochemistry Department, Tajoura Nuclear Research Center, P.O. Box-30878, Tripoli, (Libya)

    A. N. Baga

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  1. A. N. Baga
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Baga, A.N. Effect of copper(II) ions on the stability of spin adducts formed by the reaction of 5,5-dimethylpyrroline-N-oxide with hydroxyl and hydroxylalkyl radicals. Journal of Radioanalytical and Nuclear Chemistry, Articles 172, 201–212 (1993). https://doi.org/10.1007/BF02040676

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  • DOI: https://doi.org/10.1007/BF02040676

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