Skip to main content
Log in

Ion exchange separation of90Y from90Sr using ascorbic acid and nitrilotriacetic acid as eluents

  • Published:
Journal of Radioanalytical and Nuclear Chemistry Aims and scope Submit manuscript

Abstract

A simple ion exchange procedure for clean separation of the biomedically important radionuclide,90Y, in the equilibrium mixture,90Sr−90Y, has been demonstrated. Separation of90Y in the carrier-free state has been achieved by preferential elution of the radiotracer through a cation exchange resin column of Dowex-50W-X8 with freshly prepared Na-ascorbate solution of <1% concentration at pH7. The radionuclidic purity of the separated90Y has been verified by taking recourse to the studies of beta decay curves. The procedure developed has the added advantage that the complexing reagent, ascorbic acid, itself has got its own biomedical importance as vitamin C and the technique can also conveniently be used as a generator for the isotope90Y.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. P. GRILL, F. GRASS, K. BUCHTELS, J. Radioanal. Chem., 1 (1968) 179.

    Google Scholar 

  2. I. C. TALBOT, D. N. SLATKIN, R. N. ARNOT, F. H. DOYL, G. F. JOPLIN, Int.J. Appl. Radiation Isotopes, 31 (1980) 695.

    Article  Google Scholar 

  3. M. C. WHITE, F. M. DOYL, K. MASHITER, G. F. JOPLIN, Acta Endocrinol. paper No. 301 (Adv. abstract) (1981).

  4. F. KERSCHBAUMER, R. BAUER, Z. Rheumatol., 39 (1980) 127.

    PubMed  Google Scholar 

  5. J. CASSAR, F. H. DOYL, L. M. BANKS, A. JADRESIC, K. MASHITER, G. F. JOPLIN, Acta Endocrinol., 96 (1981) 295.

    PubMed  Google Scholar 

  6. M. DOHERTY, P. A. DIEPPA, Lancet, 2 (1981) 1243.

    Article  PubMed  Google Scholar 

  7. M. AUSTGEN, P. SCHLIMMER, H. WILHELM, F. TRENDELENBURG, Eur. J. Respir. Dis., 65 (1984) 64.

    PubMed  Google Scholar 

  8. R. A. SELLWOOD, I. BURN, K. FOTHIRBY, Proc. Roy. Soc. Med., 67 (1974) 854.

    PubMed  Google Scholar 

  9. G. F. JOPLIN, R. K. BLACH, H. CHENG, T. R. FRASER, Trans. Ophthal. Soc., 92 (1972) 79.

    Google Scholar 

  10. G. KNOP, Radiobiol. Radiother., 19 (1978) 644.

    Google Scholar 

  11. C. LEPSCKY, G. RISTELLI, Comit. Naz. Ricerche Nucleari CNI-13, 1959.

  12. A. BONNIN, Bull. Soc. Chim. France, 1563 (1956).

  13. J. TROIANELLO, T. T. SUGIHARA, AECU-3807, 1957.

  14. H. L. SMITH, D. C. HOFFMANN, J. Inorg. Nucl. Chem., 3 (1956) 243.

    Article  Google Scholar 

  15. R. W. PERKINS, Anal. Chem., 29 (1957) 152.

    Article  Google Scholar 

  16. T. SCHONFELD, M. WALD, M. BRUND, Proc. UN Intern. Conf. Peaceful Uses of Atomic Energy, 2nd Geneva, 28 (1958) 48.

    Google Scholar 

  17. C. W. STANLEY, P. KRUGER, Nucleonics, 14 (1956) 114.

    Google Scholar 

  18. N. R. DAS, S. N. BHATTACHARYYA, Int. J. Appl. Radiation Isotopes, 33 (1982) 171.

    Article  Google Scholar 

  19. M. CHAKRABORTY, S. M. KHOPKAR, Chromatographia, 10 (1977) 100.

    Google Scholar 

  20. P. RICHARDS, Nuclide Generator, in G. A. ANDREWS, J. W. KNISELY, H. N. WAGNER, Jr., Radioactive Pharmaceuticals. US Atomic Energy Commission, 1966.

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Das, N.R. Ion exchange separation of90Y from90Sr using ascorbic acid and nitrilotriacetic acid as eluents. Journal of Radioanalytical and Nuclear Chemistry, Articles 109, 413–418 (1987). https://doi.org/10.1007/BF02037884

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02037884

Keywords

Navigation