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On-line and low-level measurements of β-radiation in HPLC

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Abstract

The use of on-line β-detection in HPLC of radioactive-labelled samples is hampered by the time lag between the (relatively) fast separation and the slow counting. In the present approach, this difficulty is overcome by introducing a storage loop in which the eluate is temporarily stored, interspaced by a non-mixing liquid which may be the scintillator itself. The apparatus developed enables the determination of radiochromatograms which contain a total activity of ∼10 Bq.

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References

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Authors and Affiliations

  1. Netherlands Energy Research Foundation, P.O. Box 1, 1755 ZG, Petten, (The Netherlands)

    H. J. Van Nieuwkerk & H. A. Das

  2. Analytical Chemistry Laboratory, Free University, De Boelelaan 1083, 1081 HV, Amsterdam, (The Netherlands)

    U. A. Th. Brinkman & R. W. Frei

Authors
  1. H. J. Van Nieuwkerk
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  2. H. A. Das
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  3. U. A. Th. Brinkman
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  4. R. W. Frei
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Van Nieuwkerk, H.J., Das, H.A., Brinkman, U.A.T. et al. On-line and low-level measurements of β-radiation in HPLC. Journal of Radioanalytical and Nuclear Chemistry, Articles 99, 423–433 (1986). https://doi.org/10.1007/BF02037603

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  • DOI: https://doi.org/10.1007/BF02037603

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