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Studies on the differences in the effects of SeO2 and organic Se-compounds on the distribution of Hg, Co, Fe, Zn and Rb in mice by instrumental neutron activation analysis

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Abstract

The interaction of inorganic mercury (as HgCl2) with SeO2 and organic Se-compounds is compared. Instrumental neutron activation analysis (INAA) was applied as the analytical method. Organ concentrations of Hg and Se were always significantly higher after simultaneous i. p. injections with HgCl2 and Se-compounds. Especially high abundances of Se and Hg in mice organs were found after simultaneous injection with Se-methionine and HgCl2. We suggest that Hg2+ ions are bonded by selenohydryl groups of the metabolites of injected Se-compounds. Binding yield of Hg2+ ions with metabolites of Se-compounds depends upon the chemical form of injected Se-compounds. Variations in the content of Zn, Co, Fe and Rb were observed in all the investigated organs after a single injection with HgCl2 or Se-compounds. Simultaneous injection with HgCl2 and Se-compounds affects the contents of these elements in comparison with single injections.

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References

  1. G. HENDERSON, H. WU-HSING, A. ASKARI, Bioch. Pharm., 28 (1979) 429.

    Article  Google Scholar 

  2. M. BERLIN, Mercury, Handbook of the Toxicology of Metals, Elsevier, North-Holland Biomedical Press, 1979.

  3. V. SHORE, B. SHORE, Am. J. Physiol., 198 (1960) 187.

    PubMed  Google Scholar 

  4. L. MAGOS, T. W. CLARKSON, A. R. HUDSON, J. Pharmacol. Exp. Ther., 228 (1984) 478.

    PubMed  Google Scholar 

  5. K. L. NUTTALL, F. S. ALLEN, Inorg. Chim. Acta, 92 (1984) 187.

    Article  Google Scholar 

  6. S. KOSSAKOWSKI, A. GROSICKI, Bull. vet. Inst. Puŀawy, 26 (1983) 67.

    Google Scholar 

  7. G. LORENZON, E. MARAFANTE, E. SABBIONI, Biochemical Behaviour of Inorganic Mercury in the Tissues of Rats and Rabbits, Report EUR 9004 EN, 1984.

  8. M. CZAUDERNA, M. ROCHALSKA, J. Radioanal. Nucl. Chem., 97 (1986) 51.

    Article  Google Scholar 

  9. T. MAITANI, K. T. SUZUKI, Chem. Pharm. Bull., 30 (1982) 4164.

    PubMed  Google Scholar 

  10. M. G. CHERIAN, R. A. GOYER, Life Sci., 23 (1978) 1.

    Article  PubMed  Google Scholar 

  11. S. AMIEL, Nondestructive Activation Analysis, Elsevier, Amsterdam-Oxford-New York, 1981.

    Google Scholar 

  12. L. W. CHANG, The Biogeochemistry of Mercury in the Environment, Elsevier, New York, 1980.

    Google Scholar 

  13. K. KOMSTA-SZUMSKA, K. R. REUHL, D. R. MILLER, J. Toxicol. Environ. Health, 12 (1983) 775.

    PubMed  Google Scholar 

  14. A. NAGANUMA, Y. KOIJMA, A. IMURA, Res. Commun. Chem. Pathol. Pharmacol., 30 (1980) 301.

    PubMed  Google Scholar 

  15. C. C. REDDY, E. J. MASSARO, Fundam. Appl. Toxicol., 3 (1983) 431.

    PubMed  Google Scholar 

  16. T. NAKAMURA, N. ESAKI, K. SODA, H. TANAKA, Sulfur-containing Amino Acids, 3 (1980) 285.

    Google Scholar 

  17. H. G. GANTHER, Biochemistry, 10 (1971) 4089.

    Article  PubMed  Google Scholar 

  18. M. ITOH, M. EBADI, S. SWANSON, J. Neurochem., 41 (1983) 823.

    PubMed  Google Scholar 

Download references

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Authors and Affiliations

  1. Department of Chemistry, Warsaw University, Zwirki i Wigury 101, 02-089, Warsaw, (Poland)

    M. Czauderna

  2. Institute of Nuclear Chemistry and Technology, Dorodna 16, 03-195, Warsaw, (Poland)

    M. Rochalska

Authors
  1. M. Czauderna
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  2. M. Rochalska
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Czauderna, M., Rochalska, M. Studies on the differences in the effects of SeO2 and organic Se-compounds on the distribution of Hg, Co, Fe, Zn and Rb in mice by instrumental neutron activation analysis. Journal of Radioanalytical and Nuclear Chemistry, Articles 99, 265–277 (1986). https://doi.org/10.1007/BF02037586

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  • DOI: https://doi.org/10.1007/BF02037586

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