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Evaluation of disk approximation and agar dilution induction tests for demonstration of in vitro antagonism of cefotaxime by cefoxitin inEnterobacter species

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  • Current Topic Inducible Beta-Lactamases: Enzymes of Increasing Clinical Importance
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Abstract

Cefoxitin-resistant clinical isolates ofEnterobacter spp. demonstrated inducibleβ-lactamase activity in 31 of 47 (65.9%) disk approximation tests and in 32 of 52 (63.5%) agar dilution induction tests. Agreement between the two results was only 72.3%, and 80.9% of the strains were positive in at least one induction test. Lack of valid interpretive criteria preclude their routine use in the clinical laboratory.

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Authors and Affiliations

  1. Department of Microbiology and Immunology, University of Rochester School of Medicine and Dentistry, 601 Elmwood Ave., Box 710, 14642, Rochester, New York, USA

    S. W. Chandler & F. S. Nolte

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  1. S. W. Chandler
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  2. F. S. Nolte
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Chandler, S.W., Nolte, F.S. Evaluation of disk approximation and agar dilution induction tests for demonstration of in vitro antagonism of cefotaxime by cefoxitin inEnterobacter species. Eur. J, Clin. Microbiol. 6, 476–478 (1987). https://doi.org/10.1007/BF02013114

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  • DOI: https://doi.org/10.1007/BF02013114

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