Summary
Dendroaspis jamesoni venom in a dose of 12.5 μg/ml restricts the uptake of Ca+ leading to inhibition of release of Ach from the motor nerve terminals of the hemidiaphragms of rats.
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E. Karlsson, D. Eaker andL. Rydén, Toxicon10, 405 (1972).
C. C. Chang, T. F. Chen andC. Y. Lee, J. Pharmac. exp. Ther.184, 339 (1973).
M. E. Daytner andP. W. Gage, Nature New Biol.241, 246 (1973).
R. Patel andB. J. Excell, Toxicon12, 577 (1974).
E. Bulbring, Br. J. Pharmac.1, 38 (1946).
A. S. V. Burgen, F. Dickens andL. J. Zatman, J. Physiol., Lond.109, 10 (1949).
D. W. Straughan, Br. J. Pharmac.15, 417 (1960).
J. Rosenthal, J. Physiol., Lond.203, 121 (1969).
D. Weinreich, J. Physiol., Lond.212, 431 (1971).
B. Katz andR. Miledi, Proc. R. Soc. B.161, 496 (1965).
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Acknowledgment. University of Nairobi, for the research grant (No. 670-052), which supported this work. We also thank Mr. S. K. Githaiga, Government Chemist's Department, for his help in the use of the spectrophotometer.
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Telang, B.V., Ng'ang'a, J.N. & Njoroge, D. A presynaptic effect of whole venom ofDendroaspis jamesoni on the hemidiaphragm of rat. Experientia 32, 886–887 (1976). https://doi.org/10.1007/BF02003747
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DOI: https://doi.org/10.1007/BF02003747