Summary
A high molecular weight glycoprotein solubilised during platelet membrane isolation appeared to be a peripheral component of the human platelet surface and was susceptible to the action of neuraminidase when added to washed platelet suspensions.
Similar content being viewed by others
Literatur
J. H. Greenberg and G. A. Jamieson, Biochim. biophys. Acta345, 231 (1974).
J. Greenberg, M. A. Packham, J.-P. Cazenave, H. J. Reimers and J. F. Mustard, Lab. Invest.32, 476 (1975).
A. T. Nurden and J. P. Caen, Thromb. Haemostas.35, 139 (1976).
J. P. Caen, A. T. Nurden, C. Jeanneau, H. Michel, G. Tobelem, S. Levy-Toledano, Y. Sultan, F. Valensi and J. Bernard, J. Lab. Clin. Med.87, 586 (1976).
SDS-PAGE, sodium dodecyl sulphate-polyacrylamide gel electrophoresis.
C. Lombart, T. Okumura and G. A. Jamieson, FEBS Lett.41, 30 (1974).
D. R. Philips, Biochemistry11, 4582 (1972).
N. L. Baenziger, G. N. Brodie and P. W. Majerus, J. biol. Chem.247, 2723 (1972).
I. Hagen, T. Olsen and N. O. Solum, Biochim. biophys. Acta455, 214 (1976).
T. Okumura and G. A. Jamieson, Vth Int. Cong. Thromb. Haemostas. Paris, Abstr. vol., p. 474 (1975).
Kindly donated by Dr H. Schwick, Behringwerke, Marburg (BRD).
TGB-PAGE, tris: glycine buffer polyacrylamide gel electrophoresis.
J. F. Mustard and M. A. Packham, Pharmac. Rev.22, 97 (1970).
E. P. Kirby and D. C. B. Mills, J. Clin. Invest.56, 491 (1975).
M. A. Madoff, S. Ebbe and M. Baldini, J. Clin. Invest.43, 870 (1964).
A. T. Nurden, Nature251, 151 (1974).
A. J. Barber and G. A. Jamieson, J. biol. Chem.245, 6357 (1970).
A. T. Nurden, P. D. Butcher, R. Bredoux and J. P. Caen, Haemostasis3, 212 (1974).
S. J. Singer, Ann. Rev. Biochem.43, 805 (1974).
D. Aminoff, Biochem. J.81, 384 (1961).
A. T. Nurden and J. P. Caen, Br. J. Haemat.28, 253 (1974).
R. M. Zacharius, T. E. Zell, J. H. Morrison and J. J. Woodlock, Analyt. Biochem.30, 148 (1969).
T. Okumura and G. A. Jamieson, J. biol. Chem.251, 5944 (1976).
Author information
Authors and Affiliations
Additional information
Part of this work was performed at The Nuffield Institute of Comparative Medicine, Zoological Society of London, Regents Park, London (England).
Rights and permissions
About this article
Cite this article
Nurden, A.T. A peripheral high molecular weight glycoprotein located at the surface of human platelets. Experientia 33, 331–332 (1977). https://doi.org/10.1007/BF02002811
Published:
Issue Date:
DOI: https://doi.org/10.1007/BF02002811