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Characteristics of histamine and serotonin release from rat mast cells induced by thymic peptides

  • Histamine Release from Mast Cells and Basophils
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Abstract

Thymopoietin peptides release histamine and serotonin from rat mast cells. The release has the characteristics of other basic secretagogues in that it occurs rapidly, does not require extracellular Ca2+ ions, and is inhibited by benzalkonium chloride (BAC). These similarities indicate that chemically different basic compounds have common mechanisms for histamine and serotonin release from rat mast cells.

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Authors and Affiliations

  1. Department of Pharmacology, Medical Faculty, Korytkova 2, Ljubljana, Yugoslavia

    F. Erjavec & I. Ferjan

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  1. F. Erjavec
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  2. I. Ferjan
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Erjavec, F., Ferjan, I. Characteristics of histamine and serotonin release from rat mast cells induced by thymic peptides. Agents and Actions 33, 30–32 (1991). https://doi.org/10.1007/BF01993119

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  • DOI: https://doi.org/10.1007/BF01993119

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