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Intraventricular administration of isoproterenol inhibits both heat production and heat loss mechanisms in rats

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Summary

At an ambient temperature (Ta) of 8°C, intraventricular administration of isoproterenol inhibited metabolic heat production and led to hypothermia in rats. In contrast, at a Ta of 22°C and of 30°C, isoproterenol decreased cutaneous circulation and led to hyperthermia. The data indicate that isoproterenol inhibits both heat production and heat loss mechanisms in rats.

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Authors and Affiliations

  1. Department of Physiology and Biophysics, National Defense Medical Center, Taipei, Taiwan

    M. T. Lin, A. Chandra, Y. C. Fan & R. Sun

Authors
  1. M. T. Lin
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  2. A. Chandra
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  3. Y. C. Fan
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  4. R. Sun
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Additional information

This work was supported by a grant from the National Science Council of the Republic of China. The authors are grateful to Dr C.Y. Chai for pertinent advice.

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Lin, M.T., Chandra, A., Fan, Y.C. et al. Intraventricular administration of isoproterenol inhibits both heat production and heat loss mechanisms in rats. Experientia 36, 851–853 (1980). https://doi.org/10.1007/BF01978609

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  • DOI: https://doi.org/10.1007/BF01978609

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