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Intravenous injections of cholecystokinin and caerulein suppress food intake in domestic fowls

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Summary

As with various mammals, cholecystokinin (CCK) and caerulein have short-term, dose-related, inhibitory effects on feeding when injected i.v. in domestic fowls. It is estimated that in meals lasting more than about 6 min there could be time for ingested food to reach the duodenum and for the release of CCK to act as a satiety signal.

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Authors and Affiliations

  1. Agricultural Research Council's Poultry Research Centre, King's Buildings, West Mains Road, EH9 3JS, Edinburgh, Scotland

    C. J. Savory & M. J. Gentle

Authors
  1. C. J. Savory
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  2. M. J. Gentle
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Additional information

Acknowledgments. We thank I. Paul, D. Shaw and M. Thomson for technical assistance, C. McCorquodale and R. Morley Jones for designing the experiments and doing the statistical analyses, and S.J. Lucania of the Squibb Institute for Medical Research for kindly providing the synthetic CCK.

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Savory, C.J., Gentle, M.J. Intravenous injections of cholecystokinin and caerulein suppress food intake in domestic fowls. Experientia 36, 1191–1192 (1980). https://doi.org/10.1007/BF01976121

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  • DOI: https://doi.org/10.1007/BF01976121

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