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Quinolone antibacterial agents for the treatment of genitourinary tract infections

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Abstract

The fluoroquinolones have expanded the therapeutic options available for the treatment of genitourinary tract infections. Their ease of oral administration, favorable pharmacokinetics, low incidence of adverse reactions, and broad spectrum of in vitro activity against aerobic and facultative organisms make them especially suitable for treating bacteriuria, particularly when pathogens are resistant to other available oral agents. Their efficacy has also been established in the treatment of prostatitis, gonorrhea and chancroid. They have lower in vitro activity against chlamydia, ureaplasma and anaerobes, and their role in the treatment of non-gonococcal urethritis, vaginitis and acute pelvic inflammatory disease is less well established.

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  1. Ohio State University College of Medicine, Doan Hall N-1148, 410 W. 10th Avenue, 43210, Columbus, Ohio, USA

    T. J. Babinchak & R. J. Fass

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Babinchak, T.J., Fass, R.J. Quinolone antibacterial agents for the treatment of genitourinary tract infections. Eur. J. Clin. Microbiol. Infect. Dis. 8, 1111–1116 (1989). https://doi.org/10.1007/BF01975178

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