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Inflammatory models in rats depleted of endogenous precursors of prostaglandins

  • Histamine and Kinins
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Abstract

Inflammatory models in rats, depleted of prostaglandin precursors, are discussed as a novel approach to investigate anti-inflammatory drug mechanisms independent of interaction with the production of prostaglandins and to study the ambivalent (pro- or anti-inflammatory) role of endogenous prostaglandins.

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Authors and Affiliations

  1. Department of Pharmacology, Faculty of Medicine, Erasmus University, Rotterdam, P.O. Box 1738, Rotterdam, The Netherlands

    I. L. Bonta, H. Bult, M. J. Parnham & J. E. Vincent

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  1. I. L. Bonta
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  2. H. Bult
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  3. M. J. Parnham
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  4. J. E. Vincent
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Bonta, I.L., Bult, H., Parnham, M.J. et al. Inflammatory models in rats depleted of endogenous precursors of prostaglandins. Agents and Actions 8, 98–101 (1978). https://doi.org/10.1007/BF01972409

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