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The effect of hexamethonium on the secretion induced by sodium deoxycholate in the rat jejunum

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The i.v. administration of hexamethonium reduces or abolishes net water secretion induced by sodium deoxycholate in the denervated rat jejunum. The findings suggest that a local nervous reflex may be involved in bile salt-induced intestinal secretion.

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This research was sponsored by grants from the Swedish Medical Research Council (14X-2855), from the Swedish Society for Medical Sciences, from Magnus Bergvalls Stiftelse and from the Medical Faculty, University of Göteborg.

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Karlström, L., Cassuto, J., Jodal, M. et al. The effect of hexamethonium on the secretion induced by sodium deoxycholate in the rat jejunum. Experientia 37, 991–992 (1981). https://doi.org/10.1007/BF01971798

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  • DOI: https://doi.org/10.1007/BF01971798

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