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Avermectins: novel insecticides, acaricides and nematicides from a soil microorganism

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Summary

The avermectins, streptomycete-derived macrocyclic lactones originally isolated as antiparasitic agents, have also demonstrated high potencies in laboratory evaluations against insect pests in several orders, phytophagous mites and the plant-parasitic nematode,Meloidogyne. Studies suggest that the avermectins' mechanism of toxicity is fundamentally different from those associated with current natural and synthetic pesticides.

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References

  1. R. W. Burg, B. M. Miller, E. E. Baker, J. Birnbaum, S. A. Currie, R. Hartman, Y.-L. Kong, R. L. Monaghan, G. Olson, I. Putter, J. B. Tunac, H. Wallick, E. O. Stapley, R. Oiwa and S. Omura, Antimicrob. Agents Chemother.15, 361 (1979); T. W. Miller, L. Chaiet, D. J. Cole, L. J. Cole, J. E. Flor, R. T. Goegelman, V. P. Gullo, H. Joshua, A. J. Kempf, W. R. Krellwitz, R. L. Monaghan, R. E. Ormond, K. E. Wilson, G. Albers-Schonberg and I. Putter, Antimicrob. Agents Chemother.15, 368 (1979).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. J. R. Egerton, D. A. Ostlind, L. S. Blair, C. H. Eary, D. Suhayda, S. Cifelli, R. F. Riek and W. C. Campbell, Antimicrob. Agents Chemother.15, 372 (1979); G. W. Benz and J. V. Ernst, Am. J. vet. Res.40, 1198 (1979).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. D. A. Ostlind, S. Cifelli and R. Lang, Vet. Rec.105, 168 (1979).

    Article  CAS  PubMed  Google Scholar 

  4. P. S. James, J. Picton and R. F. Riek, Vet. Rec.106, 59 (1980).

    Article  CAS  PubMed  Google Scholar 

  5. C. A. Wilkins, J. Conroy, P. Ho, W. O'Shanny, P. Malatesta and J. Egerton, in preparation; C. Centurier and D. Barth, paper to the 9th Meeting of the German Society for Parasitology, 26–29 March, 1980, Giessen, FRG; C. A. Wilkins, J. Conroy, P. Ho and W. O'Shanny, paper to the American Veterinary Medical Association, 20 July, 1980, Washington, D. C.; J. L. Lancaster, J. S. Simco and R. L. Kilgore, in preparation.

  6. G. Albers-Schonberg, B. H. Arison, J. C. Chabala, A. W. Douglas, P. Eskola, M. H. Fisher, A. Lusi, H. Mrozik, J. L. Smith and R. L. Tolman, J. Am. Chem. Soc., in press (1981).

  7. C. S. Lofgren and D. Williams, USDA, Gainesville, Florida, Personal communication.

  8. R. S. Patterson and D. Dame, USDA, Gainesville, Florida, personal communication.

  9. The discovery, isolation and characterization of this metabolite will be the subject of a separate publication.

  10. L. C. Fritz, C. C. Wang and A. Gorio, Proc. natl Acad. Sci. USA76, 2062 (1979).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  11. I. S. Kass, C. C. Wang, J. P. Walrond and A. O. W. Stretton, Proc. natl Acad. Sci. USA77, 6211 (1980).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

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Author notes

  1. S. S. Ristich

    Present address: Boyce Thompson Institute for Plant Research, Cornell University, 14853, Ithaca, N. Y., USA

Authors and Affiliations

  1. Merck Sharp and Dohme Research Laboratories, Merck & Co. Inc., P. O. Box 2000, 07065, Rahway, N. J., USA

    I. Putter, J. G. Mac Connell, F. A. Preiser, A. A. Haidri, S. S. Ristich & R. A. Dybas

  2. Boyce Thompson Institute for Plant Research, Cornell University, 14853, Ithaca, N. Y., USA

    I. Putter, J. G. Mac Connell, F. A. Preiser, A. A. Haidri & R. A. Dybas

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  1. I. Putter
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  2. J. G. Mac Connell
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  3. F. A. Preiser
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  4. A. A. Haidri
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  5. S. S. Ristich
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  6. R. A. Dybas
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Putter, I., Connell, J.G.M., Preiser, F.A. et al. Avermectins: novel insecticides, acaricides and nematicides from a soil microorganism. Experientia 37, 963–964 (1981). https://doi.org/10.1007/BF01971780

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  • DOI: https://doi.org/10.1007/BF01971780

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