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Susceptibility of anaerobic bacteria to PD 131628

  • New Antimicrobial Agent
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European Journal of Clinical Microbiology and Infectious Diseases Aims and scope Submit manuscript

Abstract

The in vitro activity of PD 131628 against anaerobic cocci,Propionibacterium acnes, Clostridium perfringens, Clostridium difficile, Bacteroides fragilis, Bacteroides spp. and fusobacteria was determined by the agar dilution method. This activity was compared with that of ciprofloxacin, piperacillin, cefoxitin, imipenem, clindamycin, metronidazole and chloramphenicol. PD 131628, imipenem, clindamycin, metronidazole and chloramphenicol were the most active agents tested.

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References

  1. Cohen MA, Huband MD, Mailloux GD, Yoder SL, Roland GE, Domagala JM, Heifetz CL In vitro antibacterial activities of PD 131628, a new 1,8-naphthyridine anti-infective agent. Antimicrobial Agents and Chemotherapy 1991, 35: 141–146.

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  2. Holdeman LV, Cato EP, Moore WEC Anaerobe laboratory manual, 4th ed. Virginia Polytechnic Institute and State University, Blacksburg, VA, 1977, p. 1–156.

    Google Scholar 

  3. Dornbusch K, Nord CE, Olsson-Liljequist B Antibiotic susceptibility of anaerobic bacteria with special reference toBacteroides fragilis. Scandinavian Journal of Infectious Diseases 1979, 19: 17–25.

    PubMed  Google Scholar 

  4. National Committee for Clinical Laboratory Standards Methods for antimicrobial susceptibility testing of anaerobic bacteria, 2nd ed. NCCLS Document M11-A2. National Committee for Clinical Standards, Villanova, PA, 1990.

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Authors and Affiliations

  1. Department of Microbiology, Huddinge University Hospital, Karolinska Institute, S-141 86, Huddinge, Sweden

    C. E. Nord & A. Hagelbäck

  2. National Bacteriological Laboratory, S-105 21, Stockholm, Sweden

    C. E. Nord

Authors
  1. C. E. Nord
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  2. A. Hagelbäck
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Nord, C.E., Hagelbäck, A. Susceptibility of anaerobic bacteria to PD 131628. Eur. J. Clin. Microbiol. Infect. Dis. 11, 68–71 (1992). https://doi.org/10.1007/BF01971277

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  • DOI: https://doi.org/10.1007/BF01971277

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