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Inhibitors of the acrosomal proteinase acrosin: Human urinary trypsin inhibitor (UTI) and 4-(2-carboxyethyl) phenyl trans 4-aminomethylcyclohexanecarboxylate hydrochloride (DV-1006)

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Summary

Human urinary trypsin inhibitor (UTI) and (4-(2-carboxyethyl) phenyl trans 4-aminoethylcyclohexanecarboxylate hydrochloride (DV-1006) competitively inhibited the human acrosomal proteinase acrosin; Ki values were 1.2×10−8M and 9.4×10−7 M, respectively.

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Authors and Affiliations

  1. Biochemistry Section, Michael Reese Research Foundation, 60616, Chicago, Illinois, USA

    H. Sumi & N. Toki

  2. Department of Dermatology, Hiroshima University School of Medicine, 734, Hiroshima, Japan

    H. Sumi & N. Toki

Authors
  1. H. Sumi
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  2. N. Toki
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Sumi, H., Toki, N. Inhibitors of the acrosomal proteinase acrosin: Human urinary trypsin inhibitor (UTI) and 4-(2-carboxyethyl) phenyl trans 4-aminomethylcyclohexanecarboxylate hydrochloride (DV-1006). Experientia 36, 1103–1104 (1980). https://doi.org/10.1007/BF01965994

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