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Alteration of an anticholinergic effect by bicarbonate

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Abstract

With isolated strips of guinea-pig gut in vitro atropine in shown to be a weaker acetylcholine-antagonist when tested in bicarbonate-free solutions than in solutions containing bicarbonate. The reliability of this statement is checked in various respects.

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References

  1. J. Marti, W. Stamm andK. Bucher,Zum Einfluss der Kohlensäure auf Pharmakonwirkungen, Helv. physiol. pharmacol. Acta14, 37–49 (1956).

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Authors
  1. K. Bucher
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  2. T. Horiuchi
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Bucher, K., Horiuchi, T. Alteration of an anticholinergic effect by bicarbonate. Agents and Actions 4, 410–412 (1974). https://doi.org/10.1007/BF01964944

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  • DOI: https://doi.org/10.1007/BF01964944

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