Summary
A method has been developed for the assay of arylsulfatase C in tissue extracts containing arylsulfatases A and B. Significant variation of enzyme activity was observed among 26 inbred murine strains. Activity differences were apparent at all stages evaluated between 1 and 70 days postnatal age. Arylsulfatase C from representative high- and low-activity strains exhibited similar Michaelis constants, temperature optima, pH optima, thermostabilities and inhibitor profiles.
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This work was supported in part by Biomedical Sciences Support Grant: HEW PHS RR 07030.
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Nelson, K., Daniel, W.L. Interstrain variation of murine arylsulfatase C. Experientia 35, 309–310 (1979). https://doi.org/10.1007/BF01964317
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DOI: https://doi.org/10.1007/BF01964317