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Impaired amylase release from the parotid gland of rats treated with reserpine

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Summary

Using an automated system for the analysis of amylase, the release of this enzyme was compared in superfused parotid gland segments from control and reserpine treated rats. Stimulant-evoked amylase release was delayed and of smaller magnitude in the glands of the treated animals and a reduction of the transmembrane K+ gradient caused a smaller and short lasting reduction in Ach-evoked release of amylase in the glands from these animals.

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Author notes

  1. J. R. Martinez

    Present address: Department of Child Health, University of Missouri School of Medicine, 65212, Columbia, Missouri, USA

Authors and Affiliations

  1. Department of Physiology, University of Dundee Medical School, DD1 4HN, Dundee, Scotland

    J. R. Martinez & O. H. Petersen

Authors
  1. J. R. Martinez
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  2. O. H. Petersen
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Additional information

This work was supported by grants from the Cystic Fibrosis Research Trust (U.K.), Cystic Fibrosis Foundation (USA) and University of Missouri.

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Martinez, J.R., Petersen, O.H. Impaired amylase release from the parotid gland of rats treated with reserpine. Experientia 35, 1343–1345 (1979). https://doi.org/10.1007/BF01963998

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  • DOI: https://doi.org/10.1007/BF01963998

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