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Studies on the cytochemical localization of adenylate-cyclase activity inDugesia lugubris s.l.

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Summary

The localization of adenylate-cyclase activity inDugesia lugubris s.l. has been investigated cytochemically using 5′-adenylyl-imidodiphosphate as substrate. The enzyme was localized in mucous gland cells, in rhabdite cells, in intercellular spaces and also in nerve endings of this planarian. The presence of adenylate-cyclase on the membrane suggests that it might mediate different stimulus-secretion coupling by increasing cyclic AMP synthesis in specialized areas of the planarian.

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Authors and Affiliations

  1. Institutes of Normal Anatomy in the Faculties of Veterinary Medicine and of Biochemistry, Faculty of Pharmacy, University of Perugia, I-06100, Perugia, Italy

    Rita Pascolini, Anna Maria Gargiulo, A. Spreca & A. Orlacchio

  2. Istituto di Chimica Biologica, Facoltà di Farmacia, via del Liceo, I-06100, Perugia, Italy

    A. Orlacchio

Authors
  1. Rita Pascolini
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  2. Anna Maria Gargiulo
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  3. A. Spreca
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  4. A. Orlacchio
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Additional information

Supported in part by a grant from Consiglio Nazionale delle Ricerche, Rome.

Acknowledgments. This work was performed with the technical assistence of the laboratory of Electron Microscopy of the University of Perugia.

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Pascolini, R., Gargiulo, A.M., Spreca, A. et al. Studies on the cytochemical localization of adenylate-cyclase activity inDugesia lugubris s.l.. Experientia 35, 1315–1317 (1979). https://doi.org/10.1007/BF01963980

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