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Immunochemical identity of dipeptidyl aminopeptidase IV from pig serum, liver, submaxillary gland and kidney

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Summary

The enzymes which were extracted by autodigestion from the microsomal fractions of the pig kidney, liver and submaxillary gland and from the serum showed an immunochemical identity by a double immunodiffusion test. But the kidney enzyme had a different pI-value from the pI-values of the enzymes of other organs.

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This investigation was supported by a grant from the Ministry of Education, Japan to K. M. F. We would like to thank Dr Toshiharu Nagatsu (Department of Life Chemistry, Graduate School at Nagatsuta, Tokyo Institute of Technology, Yokohama, Japan) for helpful suggestions, Mr Moritoshi Sato (Matsumoto Meat Inspection Station, Matsumoto, Japan) for their generous supply of pig organs and Ajinomoto Co. Inc., Tokyo, Japan, for the gift of Gly-Pro-p-nitroanilide tosylate. Technical assistance of Miss K. Yanagisawa is gratefully acknowledged.

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Fukasawa, K.M., Fukasawa, K. & Harada, M. Immunochemical identity of dipeptidyl aminopeptidase IV from pig serum, liver, submaxillary gland and kidney. Experientia 35, 1142–1143 (1979). https://doi.org/10.1007/BF01963248

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