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Susceptibility of streptomycin-resistantMycobacterium tuberculosis strains to amikacin

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Abstract

A total of 585Mycobacterium tuberculosis strains isolated during a three-year period in Sweden were tested for in vitro susceptibility to amikacin in comparison with streptomycin. Resistance to streptomycin was seen in 27 of the isolates (4.6 %). These isolates had been obtained from 22 patients, a majority of which were non-European immigrants. All but one of the streptomycin-resistant isolates were susceptible to amikacin. None of 263 streptomycin-susceptible isolates tested was resistant to amikacin. Amikacin appears to be an alternative to streptomycin in the treatment of patients with streptomycin-resistantMycobacterium tuberculosis.

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Authors and Affiliations

  1. Department of Bacteriology, National Bacteriological Laboratory, 105 21, Stockholm, Sweden

    S. E. Hoffner & G. Källenius

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  1. S. E. Hoffner
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  2. G. Källenius
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Hoffner, S.E., Källenius, G. Susceptibility of streptomycin-resistantMycobacterium tuberculosis strains to amikacin. Eur. J. Clin. Microbiol. Infect. Dis. 7, 188–190 (1988). https://doi.org/10.1007/BF01963078

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  • DOI: https://doi.org/10.1007/BF01963078

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